Differential neuroproteomic and systems biology analysis of spinal cord injury [PDF]
, 2016 Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery ...
Bramlett, Helen M +8 more
core +2 more sources
Proteomic Analysis of the Mitochondrial Responses in P19 Embryonic Stem Cells Exposed to Florfenicol
Toxics, 2023 Florfenicol (FLO) has been shown to elicit diverse toxic effects in plants, insects, and mammals. Previously, our investigations revealed that FLO induced abnormal cardiac development and early embryonic mortality in chicken embryos.
Zhihua Dong +11 more
doaj +1 more source
Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria [PDF]
, 2018 Background: The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of mortality and cardiovascular disease in patients with microalbuminuria (MA) is unknown.
Currie, Gemma E. +11 more
core +2 more sources
Quantitative profiling of the human substantia nigra proteome from laser-capture microdissected FFPE tissue [PDF]
, 2020 Laser-capture microdissection (LCM) allows the visualization and isolation of morphologically distinct subpopulations of cells from heterogeneous tissue specimens.
Griesser, Eva +5 more
core +3 more sources
Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]
, 2013 The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model.
Aude-Garcia, Catherine +12 more
core +5 more sources
Proteomic Analysis of Microorganisms
International Journal of Molecular Sciences, 2022 At the early stage of the development of proteomic technologies, Escherichia coli or Saccharomyces cerevisiae were used as model microorganisms for high-throughput identification technologies, such as shotgun proteomics or 2D gel electrophoresis-based LC-MS/MS analysis [...]
openaire +2 more sources
Biomarkers of inflammatory arthritis and proteomics [PDF]
, 2013 N/
FitzGerald, Oliver +3 more
core +3 more sources
Quantitative Proteomic Analysis Reveals Changes in the Benchmark Corynebacterium pseudotuberculosis Biovar Equi Exoproteome after Passage in a Murine Host [PDF]
, 2017 Corynebacterium pseudotuberculosis biovar equi is the etiologic agent of ulcerative lymphangitis. To investigate proteins that could be related to the virulence of this pathogen, we combined an experimental passage process using a murine model and high ...
Adriano M. C. Pimenta +12 more
core +4 more sources
KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number
Molecular & Cellular Oncology, 2017 We have recently identified the first human lysine (K) acetyltransferase 2A and 2B (called KAT2A/2B; known also as GCN5/PCAF, respectively)-dependent acetylome and revealed a mechanism by which KAT2A/2B-mediated acetylation of serine/threonine polo-like ...
Marjorie Fournier, László Tora
doaj +1 more source
Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study [PDF]
, 2016 Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is currently hampered by the lack of accurate and early biomarkers for diagnosis of AKI and the
Groesdonk, Heiner +7 more
core +3 more sources