Results 141 to 150 of about 190,185 (400)

Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation

Research and Practice in Thrombosis and Haemostasis
Background: Inherited thrombophilia (IT) is a genetically determined predisposition to thromboembolic events. Beyond the well-known G20210A mutation, there has been limited research on other prothrombin mutations in the Chinese population.
Si-Yuan Wen, Fei-Fei Chen, Ji-De Chen, Pan Tao, Chi Meng, Jing Huang, Xin Kang, Wei Chen, Chang-Qing Zhou   +8 more
doaj   +1 more source

Success of transition to adult care in patients with pediatric‐onset chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Previous studies on chronic pediatric‐onset conditions have highlighted the risks of loss to follow‐up, disease progression, or therapeutic nonadherence during transition. However, very few studies have focused on liver diseases.
Sarah Mongbo, Valérie Canva, Sébastien Dharancy, Guillaume Lassailly, Alexandre Louvet, Philippe Mathurin, Nassima Ramdane, Frédéric Gottrand, Madeleine Aumar   +8 more
wiley   +1 more source

Cellular site for prothrombin synthesis

, 1960
The cell type responsible for synthesis of any of the trace plasma proteins concerned in blood coagulation has not been identified before. In this study the fluorescent antibody technique was used to find out the cellular site for prothrombin synthesis.
Marion I. Barnhart
core   +1 more source

The needle study: Machine learning as a new method for case‐finding in celiac disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite a well‐defined diagnostic work‐up, uncertainties persist regarding celiac disease (CeD) detection strategies in the general population. Machine learning (ML) algorithms offer promise in aiding medical decision‐making on clinical data.
Chiara Maria Trovato, Monica Montuori, Maria Ludovica Costanzo, Giusy Russo, Cosimo Ruggiero, Danila Volpe, Francesca Ferretti, Antonella Diamanti, Carlo Ciliberto, Salvatore Oliva   +9 more
wiley   +1 more source

Prothrombin Activation Is Increased among Asymptomatic Carriers of the Prothrombin G20210A and Factor V Arg506Gln Mutations

, 2000
SummaryThe risk of venous thrombosis is increased in individuals who carry specific genetic abnormalities in blood coagulation proteins. Among Caucasians, the prothrombin G20210A and factor V Arg506Gln (FV R506Q) mutations are the most prevalent defects ...
Kenneth Bauer, Robert Rosenberg, Samad Barzegar, Belinda Smillie, George Miller, Steve Humphries, Lily Li, Jacqueline Cooper   +7 more
core   +1 more source

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Clinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg   +3 more
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Chicken prothrombin, thrombin, and fibrinogen

, 1961
Avian blood coagulation studies revealed the mean one-stage prothrombin time of plasma from 100 chickens, 10 weeks of age, as determined with chicken brain thromboplastin, to be 11.4 seconds, compared with 10–300 seconds found by other workers; the mean
D. C. Triantaphyllopoulos, C. H. Bigland
core   +1 more source

Evidence for the involvement of superoxide in vitamin K-dependent carboxylation of glutamic acid residues of prothrombin [PDF]

, 1978
M. P. Esnouf, M R Green, H. Allen O. Hill, G. Brent Irvine, S. J. Walter   +4 more
openalex   +1 more source

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source