Results 161 to 170 of about 134,214 (298)

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

Using Preoperative Therapeutic Plasma Exchange in Lupus Anticoagulant Hypoprothrombinemia Syndrome to Achieve Hemostatic Factor II Activity: A Case Report. [PDF]

J Clin Apher
Panwar P, Yates SG, Yarborough R, Shen YM.   +3 more
europepmc   +1 more source

Performance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality Controls

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction It is recommended to detect lupus anticoagulant (LA) using two phospholipid‐dependent clotting assays, including a LA‐sensitive activated partial‐thromboplastin‐time (aPTT). Among these reagents, Staclot‐LA assay is performed on a mixture of test and normal plasma with and without hexagonal phase phospholipids.
V. Siguret, G. Jourdi, S. Melicine, L. Goubeau, Q. Pomorski, B. Joly‐Laffargue, A. Stepanian, M. Delrue, C. Bon, P. Meijer, E. Curis   +10 more
wiley   +1 more source

Is It Time to Raise the Threshold for Critically Low Fibrinogen? Insights From a Retrospective, Consecutive‐Case Cohort Study of Low Fibrinogen due to Various Causes

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Fibrinogen deficiency is an important coagulation abnormality, with diverse causes. Methods A consecutive‐case cohort study of adult and pediatric patients with low Clauss fibrinogen at four acute care hospitals was undertaken to explore findings, causes, and predictors of outcomes, including the optimal fibrinogen critical value ...
Natalie Mathews, Subia Tasneem, Mana Al Dawsari, Keona Pang, Yasmeen Abulkhair, Guillame Paré, Siraj Mithoowani, Catherine P. M. Hayward   +7 more
wiley   +1 more source

The Components of Prothrombin

Experimental Biology and Medicine, 1946
openaire   +2 more sources

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Prevalence and laboratory-associated variability of non-criteria antiphospholipid antibodies in women with pregnancy loss: A cross-sectional study. [PDF]

J Transl Autoimmun
Ding N, Wang R, Wang K, Li G, Wang F.
europepmc   +1 more source

Early Changes in Lymphocyte Counts Predict Clinical Outcomes in Hepatocellular Carcinoma Treated With Durvalumab Plus Tremelimumab

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Durvalumab plus tremelimumab (Dur/Tre) has shown promising efficacy in advanced hepatocellular carcinoma (HCC), but predictive biomarkers remain unclear. This study aimed to determine whether early changes in peripheral blood lymphocyte counts during Dur/Tre therapy can predict clinical outcomes.
Yuichi Honma, Shigeo Shimose, Takanori Ito, Issei Saeki, Joji Tani, Takanori Matsuura, Tetsu Tomonari, Yasuto Takeuchi, Nobuhito Taniki, Kyo Sasaki, Ryu Sasaki, Takeshi Hatanaka, Satoru Kakizaki, Naoki Yoshioka, Takehito Naito, Mamiko Takeuchi, Tetsuya Yasunaka, Masahiro Sakata, Hideki Iwamoto, Tomotake Shirono, Satoshi Itano, Norikazu Tanabe, Takafumi Yamamoto, Atsushi Naganuma, Yuki Kanayama, Hisamitsu Miyaaki, Sohji Nishina, Nobuhiro Nakamoto, Motoyuki Otsuka, Tetsuji Takayama, Yuzo Kodama, Hideki Kobara, Taro Takami, Hiroki Kawashima, Takumi Kawaguchi, Masaru Harada, Hepatology InVestigator Experts in Japan (HIVE‐J) Study Group   +36 more
wiley   +1 more source

Diagnostic performance of liver biochemical and hemostatic markers for assessing cirrhosis severity in chronic hepatitis B. [PDF]

BMC Gastroenterol
Luo C, Luo Y, Li Q, Zhou X, Luo J.
europepmc   +1 more source