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Acquired factor V deficiency in an elderly hemodialysis patient: a case report and literature review. [PDF]

open access: yesBMC Nephrol
Hane A   +6 more
europepmc   +1 more source

Congenital Prothrombin Deficiency

Seminars in Thrombosis and Hemostasis, 2009
Prothrombin deficiency is among the rarest inherited coagulation disorders, with a prevalence of approximately 1:2,000,000. Two main phenotypes can be distinguished: (1) hypoprothrombinemia (type I deficiency), characterized by concomitantly low levels of activity and antigen; and (2) dysprothrombinemia (type II deficiency), characterized by the normal
Lancellotti, Stefano   +1 more
openaire   +3 more sources

The Prothrombin Gene

Pathophysiology of Haemostasis and Thrombosis, 1986
Using recombinant DNA techniques, DNA fragments coding for bovine prothrombin mRNA have been cloned and characterized. Structural studies have revealed that prothrombin mRNA encodes a precursor protein having an amino-terminal extension of 43 amino acid residues.
R T, MacGillivray, D M, Irwin
openaire   +2 more sources

Hereditary Prothrombin Deficiency

New England Journal of Medicine, 1970
Abstract Quantitative immunologic assay of the plasma of the proposita in a family with hereditary prothrombin deficiency demonstrated the defect to be due to an actual deficiency of the prothrombi...
H E, Kattlove, S S, Shapiro, M, Spivack
openaire   +2 more sources

Activation of Prothrombin

American Journal of Physiology-Legacy Content, 1956
In the activation of a prothrombin solution, only part of the prothrombin becomes biothrombin, some becomes autoprothrombin I and some becomes autoprothrombin II. Thrombin-thrombin is also obtained, and perhaps other derivatives of prothrombin are formed. Prothrombin thus has multiple potentialities and these can be developed in diverse ways.
J A, PENNER, W H, SEEGERS
openaire   +2 more sources

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