Results 211 to 220 of about 105,223 (244)

Activation of Prothrombin

American Journal of Physiology-Legacy Content, 1958
In experiments with purified biothrombin, it was found that strong solutions of sodium citrate or protamine sulfate (0.1% w/v) or purified platelet factor 3 depress the esterase activity and leave the clotting power unaltered. Apparently a depression of esterase activity is beneficial for the autocatalytic activation of purified prothrombin.
R H, LANDABURU, W H, SEEGERS
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Prothrombin madrid : A new familial abnormality of prothrombin

Thrombosis Research, 1979
Abstract An abnormal prothrombin has been detected in a 13 yr-old girl, with history of excessive bleeding. Prothrombin time and activated partial thromboplastin time were markedly prolonged. Prothrombin activity was very low when measured by biological assay using either physiological activators (3% by one stage assay and 20 US u/ml by two stage ...
A, Bezeaud, M C, Guillin, F, Olmeda, M, Quintana, N, Gomez   +4 more
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Prothrombin Time Standardization

Acta Clinica Belgica, 1987
SummaryAs recommcndcd by the proper authorities, the prothrombin time results for patients under oral anticoagulant therapy arc reported by our laboratory in International Normalized Ratios (I.N.R.).For the calculation of the INR-values we use a calibration factor, the International Sensitivity Index (I.S.I.), provided by the manufacturer of the ...
L, Hameeuw, L, Sierens, A, Lust
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Prothrombin Segovia: A new congenital abnormality of prothrombin

Scandinavian Journal of Haematology, 1986
A family with a new congenital dysprothrombinemia is presented. The propositus is a 21‐yr‐old man who presented simultaneously with hemartrosis of the left knee and an extensive hematoma following a minor trauma. Prothrombin time and activated partial thromboplastin time were prolonged.
E, Rocha, J A, Paramo, C, Bascones, P R, Fisac, B, Cuesta, J, Fernandez   +5 more
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Prothrombin Poissy: a new variant of human prothrombin

British Journal of Haematology, 1987
SummaryA new congenital dysprothrombinaemia is described in a newborn baby girl who presented severe bleeding from the second day of life. Routine coagulation tests showed very prolonged prothrombin time and activated partial thromboplastin time with about 2% prothrombin activity in a one‐stage assay.
M D, Dumont, J, Tapon-Bretaudiere, A M, Fischer, A, Bros, J, Chassevent, J P, Aufeuvre   +5 more
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Antibodies to prothrombin

Lupus, 2012
Research on antiphospholipid antibodies (aPL) and the thrombotic manifestations associated with these antibodies has grown since the description of anticardiolipin antibodies (aCL) by Harris and colleagues in the early 1980s. Antiprothrombin (aPT) antibodies are commonly detected by ELISA, using irradiated plates (aPT) or prothrombin in complex with ...
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Electroimmunoassay of prothrombin

Thrombosis Research, 1987
Electroimmunoassay of normal (10-Gla) and Gla-deficient prothrombins containing 0 to 9 Gla (gamma-carboxyglutamyl) residues performed in EDTA against anti- (normal) prothrombin showed that each of the Gla-deficient proteins contained as much antigenic activity as does the normal molecule. In the presence of Ca2+, however, normal prothrombin appeared to
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Prothrombin Time

Annals of Internal Medicine, 1982
B A, Cooper, M, Leznoff
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Prothrombin and Fibrinolysin

Science, 1946
W H, SEEGERS, E C, LOOMIS
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Formation of Prothrombin Derivatives From Purified Prothrombin

American Journal of Physiology-Legacy Content, 1951
W H, SEEGERS, E B, ANDREWS, R I, McCLAUGHRY   +2 more
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