Results 211 to 220 of about 219,018 (388)

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

Alimentary Pharmacology &Therapeutics, EarlyView.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang, Jinghua Cui, Yixin Hou, Lining Guo, Hai Li, Guiqin Zhou, Xiaojing Wang, Bingbing Zhu, Ke Shi, Yi Zhang, Yufei Bi, Yanqiu Li, Lina Sun, Ying Feng, Jing Yuan, Xianbo Wang   +15 more
wiley   +1 more source

Heating up the Blunts: Prothrombin Activation, with Factor Va as an Obligate Cofactor, Is the Dominant Procoagulant Mechanism of Blunt-Nosed Viper Venoms (<i>Macrovipera</i> Species). [PDF]

Toxins (Basel)
Champagne PS, Seneci L, Fry BG.
europepmc   +1 more source

PROTHROMBIN IN ENZYMOLOGY, THROMBOSIS AND HEMOPHILIA [PDF]

, 1968
G. I. C. Ingram
openalex   +1 more source

Citrate anticoagulation for extracorporeal circuits: Effects on whole blood coagulation activation and clot formation [PDF]

, 2001
Calatzis, A., Schiffl, Helmut, Schramm, W., Spannagl, M., Toepfer, Marcel   +4 more
core   +1 more source

Guidelines from the expert advisory committee on the Safety of Blood, Tissues and Organs (SaBTO) on patient consent and shared decision‐making for blood transfusion

British Journal of Haematology, EarlyView.
The key points to be discussed with a patient when obtaining consent to transfusion are the reason for the transfusion, the benefits and risks of transfusion, the possible alternatives to transfusion, the process for transfusion, any specific transfusion requirements that the patient may have, the consequences of refusing transfusion and the ability to
Michael F. Murphy, Damien Carson, Anwen Davies, Stephanie Ditcham, Graham Donald, Roger Graham, Lizzie Hutchinson, Paul Kerr, Denise McKeown, John Moppett, Shruthi Narayan, Paolo Polzella, Ella Poppitt, Megan Rowley, Tracey Shackleton, Julie Staves, James Neuberger   +16 more
wiley   +1 more source

The predictive model and risk factor identification for peripheral vascular disease and diabetic foot in diabetes based on machine learning models and explainable algorithms. [PDF]

Medicine (Baltimore)
Pan Y, Tao G, Chen B, Zheng C, Li G.
europepmc   +1 more source

The linker connecting the two kringles plays a key role in prothrombin activation

Proceedings of the National Academy of Sciences of the United States of America, 2014
N. Pozzi, Zhiwei Chen, L. Pelc, D. B. Shropshire, E. Di Cera   +4 more
semanticscholar   +1 more source

Abnormal activation of a human prothrombin variant: Prothrombin barcelona [PDF]

FEBS Letters, 1978
Dominique Labie, F. Josso, Richard Benarous, Marie-Josèphe Rabiet   +3 more
openaire   +3 more sources

Activated prothrombin complex concentrate for dabigatran‐associated bleeding

British Journal of Haematology, 2014
S. Schulman, B. Ritchie, Jennifer K. Goy, S. Nahirniak, M. AlMutawa, Shari Ghanny   +5 more
semanticscholar   +1 more source

Tumor Endothelial Cells Induce M2 Macrophage Polarization via IL‐4, Enhancing Tumor Growth in Hepatocellular Carcinoma

Cancer Science, EarlyView.
Tumor endothelial cells (TECs) promote the polarization of macrophages to M2 subtype by secreting IL‐4. Downregulation of IL‐4 in TECs suppressed M2 polarization and tumor progression. A high abundance of both TECs and M2 macrophages in HCC specimens is associated with poor prognosis.
Daijiro Matoba, Takehiro Noda, Shogo Kobayashi, Yoshihiro Sakano, Kenichi Matsumoto, Chihiro Yamanaka, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Hisashi Wada, Yuichiro Doki, Hidetoshi Eguchi   +17 more
wiley   +1 more source