The progress of prothrombin time measurement
Hematology Reports, 2009 Warfarin is the most widely used medicine for oral anticoagulant therapy (OAT). It inhibits the synthesis of coagulation factors II, VII, IX, and X in the liver and results in the production of inactive or partially active versions of these factors ...
Juha Eero Horsti
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Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article [PDF]
Thrombosis Journal, 2021 The antithrombotic effect of vitamin K antagonists (VKA) depends on controlled lowering of the activity of factors (F) II and X whereas reductions in FVII and FIX play little role. PT-INR based monitoring, however, is highly influenced by FVII, which has
Pall T. Onundarson +3 more
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Prognostic Role of Prothrombin Time Activity, Prothrombin Time, Albumin/Globulin Ratio, Platelets, Sex, and Fibrinogen in Predicting Recurrence-Free Survival Time of Renal Cancer [PDF]
Cancer Management and Research, 2020 Zichen Bian,1,* Jialin Meng,1,* Qingsong Niu,1 Xiaoyan Jin,2 Jinian Wang,3 Xingliang Feng,1 Hong Che,4 Jun Zhou,1 Li Zhang,1 Meng Zhang,1,5 Chaozhao Liang1 1Department of Urology, The First Affiliated Hospital of Anhui Medical University; Anhui Province ...
Bian Z +10 more
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Prothrombin time predicting time-dependent and risk-stratified mortality in polytrauma patients [PDF]
International Journal of Emergency MedicineBackground Polytrauma is associated with a high mortality rate and often accompanied by coagulopathy. Prothrombin time (PT) is a prognostic factor for mortality in polytrauma patients. The aim was to analyze the time- and severity-dependent role of PT in
Philipp Vetter +5 more
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Diagnostic performances of D-dimer, prothrombin time, and red blood cell distribution width for coronary artery lesion in children with acute stage Kawasaki disease [PDF]
Frontiers in Pediatrics, 2023 AimTo evaluate the performances of D-dimer, prothrombin time (PT), and red blood cell distribution width (RDW) for the diagnosis of coronary artery lesion (CAL) in acute stage Kawasaki disease (KD).MethodsBetween January 2018 and January 2021, a total of
Qi-Gai Yin +5 more
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OPTIMIZATION OF THE EVALUATION METHOD OF THE PERFORMANCE OF THERAPY USING INDIRECT ACTION ANTICOAGULANTS [PDF]
Biotechnologia Acta, 2022 Aim. Treatment by indirect anticoagulants (vitamin K antagonists) requires a personalized approach for controlling the overall level of prothrombin and the accumulation of its decarboxylated forms.
D. S. Korolova +6 more
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RADS Journal of Biological Research & Applied Science, 2021 Background: Diabetic patients are at higher risk of cardiovascular disease than non-diabetics. Elevated glucose level in type 2 Diabetes mellitus (T2DM) can induce variations in blood composition and blood vesicles, which lead towards coagulation ...
Sajjad Ahmad +5 more
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Evaluation of Routine Coagulation Parameter in Suspected Acute Myocardial Infarction Patients Attending Emergency Department of Tertiary Care Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Heart attack in medical terminology is generally called as Acute Myocardial Infarction (AMI). When blood flow is abruptly cut-off to the heart muscle, it damages the myocardial tissue.
Mritunjay Kumar Mishra +2 more
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Majalah Kedokteran Andalas, 2021 Pendahuluan: Hematokrit (Ht) yang tinggi merupakan salah satu faktor interferensi pemeriksaan hemostasis yang sering luput dari perhatian. Penurunan volume plasma relatif terhadap keseluruhan darah pada hematokrit yang tinggi akan meningkatkan rasio ...
Hevrina Yufani, Zelly Dia Rofinda
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Effect of Pre-Analytic Variables on Prothrombin Time and Activated Partial Thromboplastin Time [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Inadvertent inappropriate coagulation tests results are reported frequently inspite of using automated instruments and quality assurance measures, mostly due to pre analytical errors associated with sample collection and processing.
Garima M Anandani, Swati B Parikh
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