The progress of prothrombin time measurement
Warfarin is the most widely used medicine for oral anticoagulant therapy (OAT). It inhibits the synthesis of coagulation factors II, VII, IX, and X in the liver and results in the production of inactive or partially active versions of these factors ...
Juha Eero Horsti
doaj +3 more sources
Prothrombin time in retinitis pigmentosa
The prothrombin time was recorded for 87 primary retinitis pigmentosa (RP) patients belonging to three different clinical categories. All categories showed prothrombin time higher than normal.
Vinchurkar Manisha
doaj +1 more source
Prothrombin time predicting time-dependent and risk-stratified mortality in polytrauma patients [PDF]
Background Polytrauma is associated with a high mortality rate and often accompanied by coagulopathy. Prothrombin time (PT) is a prognostic factor for mortality in polytrauma patients. The aim was to analyze the time- and severity-dependent role of PT in
Philipp Vetter +5 more
doaj +2 more sources
The development of a novel native prothrombin assay for the more efficient management of oral anticoagulation therapy [PDF]
Disturbances of the natural balance between pro-coagulant and anticoagulant systems, due to hereditary or acquired factors may result in haemorrhagic or thrombotic diseases.
Sylvester, Adrian Jose
core +7 more sources
Should we Test the Prothrombin Time in Anticoagulated Epistaxis Patients? [PDF]
Epistaxis is one of the most frequent emergencies in rhinology. Patients using anticoagulative medication are at increased risk for epistaxis. We evaluated the prothrombin time and the international normalized ratio (INR) in anticoagulated epistaxis ...
Michael B. Soyka M.D. +1 more
doaj +2 more sources
A note on the prothrombin time abnormality in the patients with amebic liver abscess
Amebic liver abscess is reported worldwide and can present with a a wide spectrum of clinical manifetations. Similar to the other liver diseases, the prothrombin time abnormality can be seen in the patients with amebic liver abscess.
Viroj Wiwaniikit +2 more
doaj +1 more source
OPTIMIZATION OF THE EVALUATION METHOD OF THE PERFORMANCE OF THERAPY USING INDIRECT ACTION ANTICOAGULANTS [PDF]
Aim. Treatment by indirect anticoagulants (vitamin K antagonists) requires a personalized approach for controlling the overall level of prothrombin and the accumulation of its decarboxylated forms.
D. S. Korolova +6 more
doaj +1 more source
A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]
The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Lowe, G.D.O. +9 more
core +5 more sources
Background: Diabetic patients are at higher risk of cardiovascular disease than non-diabetics. Elevated glucose level in type 2 Diabetes mellitus (T2DM) can induce variations in blood composition and blood vesicles, which lead towards coagulation ...
Sajjad Ahmad +5 more
doaj +1 more source
Evaluation of Routine Coagulation Parameter in Suspected Acute Myocardial Infarction Patients Attending Emergency Department of Tertiary Care Hospital [PDF]
Introduction: Heart attack in medical terminology is generally called as Acute Myocardial Infarction (AMI). When blood flow is abruptly cut-off to the heart muscle, it damages the myocardial tissue.
Mritunjay Kumar Mishra +2 more
doaj +1 more source

