Results 141 to 150 of about 109,952 (303)

Identification of Coagulation Phenotypes Using Viscoelastic and Conventional Assays During Veno‐Venous Extracorporeal Membrane Oxygenation: A Hierarchical Clustering Analysis

open access: yesArtificial Organs, EarlyView.
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada   +9 more
wiley   +1 more source

Short Inter‐Treatment Interval Treatment With Artificial Liver Support System Reduces 90‐Day Transplant‐Free Mortality in Patients With Hepatitis B Virus–Related Acute‐On‐Chronic Liver Failure: A Retrospective Observational Study

open access: yesArtificial Organs, EarlyView.
ALSS short inter‐treatment interval treatment (patients received two ALSS treatments within 48 h) correlates with improved liver function and 90‐day transplant‐free survival of HBV‐ACLF. This result provides a certain theoretical basis for the timing and time interval of ALSS for HBV‐ACLF, enriches the models and contents of ALSS treatment for HBV‐ACLF,
Jingjie Fu   +4 more
wiley   +1 more source

The effect of phenobarbital upon the prolonged prothrombin time in parenchymal liver disease

open access: yes, 1977
Eight patients with parenchymal liver disease who had prolonged prothrombin time unresponsive to vitamin K1 were given phenobarbital 60 to 100 mg daily. Prothrombin time decreased in 6 to 19 days to near normal or normal values.
Kaplaman E., Ozer F.L.
core  

Extracorporeal Albumin Dialysis (OPAL) as Novel Therapeutic Bridging Option in Posthepatectomy Liver Failure

open access: yesArtificial Organs, EarlyView.
Extracorporeal albumin dialysis (OPAL) effectively reduces bilirubin and improves other laboratory markers in posthepatectomy liver failure, particularly in secondary forms. It may serve as a bridging therapy to support hepatic recovery in critically ill patients, although prospective studies are needed to confirm its impact on survival.
Dorian Marckmann   +16 more
wiley   +1 more source

Temporal Association Between COVID‐19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi   +6 more
wiley   +1 more source

Prothrombin Time and Coagulation Factor IX as Hemostatic Risk Markers for Legg- Calvé-Perthes Disease. [PDF]

open access: yesClin Appl Thromb Hemost, 2023
Hernández-Zamora E   +5 more
europepmc   +1 more source

HUBUNGAN HIPERGLIKEMIA DENGAN PROTHROMBIN TIME PADA MENCIT (Mus musculus) YANG DIINDUKSI ALOKSAN

open access: yes, 2014
Komplikasi kronik DM (mikroangiopati dan makroangiopati) terjadi akibat disfungsi endotel yang disebabkan oleh berbagai proses patogenesis seperti hiperglikemia, stres oksidatif, peningkatan jumlah asam lemak bebas, Protein Kinase C β dan defek sekresi
MUHAMMAD, IBNU MALIK
core  

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden   +3 more
wiley   +1 more source

Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley   +1 more source

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