Results 121 to 130 of about 143,882 (299)

Estetrol‐based combined oral contraceptives: A systematic review of clinical outcomes

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
This systematic review summarizes clinical outcomes of estetrol‐containing combined oral contraceptives, showing reliable contraceptive efficacy, predictable bleeding patterns, improved well‐being, and a favorable hemostatic and metabolic profile, suggesting a promising and potentially safer alternative to ethinylestradiol‐based formulations.
Mathilde Råberg   +3 more
wiley   +1 more source

Fatal intracranial hemorrhage in a newborn with factor VII deficiency

open access: yesThe Turkish Journal of Pediatrics, 1996
Factor VII deficiency is a rare congenital coagulopathy. Prolonged prothrombin time with normal partial thromboplastin time indicates factor VII deficiency. For the definitive diagnosis, the specific factor VII level should be investigated.
R Uçsel   +4 more
doaj  

joineR: Joint modelling of repeated measurements and time-to-event data [PDF]

open access: yes, 2012
The joineR package implements methods for analysing data from longitudinal studies in which the response from each subject consists of a time-sequence of repeated measurements and a possibly censored time-toevent outcome.
Diggle, Peter   +5 more
core  

Identification of Coagulation Phenotypes Using Viscoelastic and Conventional Assays During Veno‐Venous Extracorporeal Membrane Oxygenation: A Hierarchical Clustering Analysis

open access: yesArtificial Organs, EarlyView.
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada   +9 more
wiley   +1 more source

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova   +6 more
wiley   +1 more source

Central Nervous System Bleeding in Children With Haemophilia in Limited Resource

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Central nervous system (CNS) bleeding in children with haemophilia is a life‐threatening complication that may cause severe neurological sequelae or death. In resource‐limited settings, where prophylaxis is not universally accessible, its patterns and outcomes may differ from those in high‐income countries.
Patcharee Komvilaisak   +5 more
wiley   +1 more source

The effect of portacaval transposition on carbohydrate metabolism: Experimental and clinical observations [PDF]

open access: yes, 1965
An investigation was conducted of the influence of portacaval transposition upon carbohydrate metabolism in 45 dogs. In 17 dogs, hepatic glycogen content was measured before and from 45 to 75 days after transposition.
Faris, TD   +6 more
core  

Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley   +1 more source

FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives

open access: yesHaemophilia, EarlyView.
ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita   +2 more
wiley   +1 more source

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