Results 101 to 110 of about 109,952 (303)

A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Clinical Case Reports
Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant.
Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg   +3 more
doaj   +1 more source

Resolving a Complex Neonatal Phenotype by Rapid Trio Whole‐Genome Sequencing: A De Novo 11q14.3–q22.3 Deletion and a Splicing‐Altering Synonymous ANK1 Variant

Journal of Clinical Laboratory Analysis, EarlyView.
Clinical utility of trio WGS and time metrics in a neonate with congenital anomalies and hemolytic anemia. ABSTRACT Background Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing.
Hyun‐Woo Lee, Ja‐Hyun Jang, Beom Hee Lee, Hee‐Jeong Youk, Eun Sun Kim, Kee Hyun Cho, Yun Sil Chang, Heui Seung Jo, Mi‐Ae Jang   +8 more
wiley   +1 more source

The changes in the fibrinogen concentration and coagulation pathways in winter and summer in cattle [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2013
Fibrinogen is an important coagulation factor and a positive acute phase protein and its levels increases in cases of inflammation infection and stress. The present research was done to determine whether the fibrinogen concentration, prothrombin time (PT)
ameneh khoshvaghti
doaj  

A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs)

Upsala Journal of Medical Sciences, 2017
Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC procedure: Zafena’s Simple Simon™ PT-INR, a room-temperature, wet-chemistry prothrombin time method of
Tomas L. Lindahl, Kerstin Arbring, Maria Wallstedt, Mats Rånby   +3 more
doaj   +1 more source

Pengaruh Variasi Volume Darah Pada Pemeriksaan Prothrombin Time [PDF]

, 2019
Prothrombin time adalah tes skrining laboratorium yang memantau faktor-faktor di jalur ekstrinsik seperti Faktor I, II, V, VII, dan X. Subjek penelitian sebanyak 9 orang, pada setiap subjek penelitian dilakukan pemeriksaan skrining awal yaitu ...
Pinat, Metusalak M.
core  

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source

The prothrombin time/international normalized ratio (PT/INR) Line: derivation of local INR with commercial thromboplastins and coagulometers--two independent studies

, 2011
The WHO scheme for prothrombin time (PT) standardization has been limited in application, because of its difficulties in implementation, particularly the need for mandatory manual PT testing and for local provision of thromboplastin international ...
Jespersen, J, Ibrahim, S, Pattison, A, L. POLLER, Keown, M., Jespersen, J., J. JESPERSEN, A. PATTISON, Ibrahim, S.; id_orcid, Pattison, A., S. IBRAHIM, M. KEOWN, Poller, L, Poller, Leon, Keown, M   +14 more
core   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

Journal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu, Jie Shi, Fengjuan Wang, Liang Ma, Huangang Hu, Li Zhang, Jie Song, Heng Jin, Dingwei Yang, Xiaoqin Guo, Haojun Fan, Qi Lv   +11 more
wiley   +1 more source

Determination of prothrombin time by the Ovren method in recipients after liver transplantation from a donor diagnosed with brain death

Український журнал клінічної хірургії
Objective. To evaluate a new method for diagnosing the state of the hemostatic system in patients with hepatobiliary pathology who underwent liver transplantation from a donor diagnosed with brain death. Materials and Methods.
R. A. Zatsarynnyi, O. Y. Khomenko, A. Y. Lysenko   +2 more
doaj   +1 more source