Results 81 to 90 of about 143,882 (299)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Antithrombotic activity of Mentha longifolia in animal model

Bangladesh Journal of Pharmacology, 2018
The present research work was conducted to appraise the antithrombotic activity of Mentha longifolia using in vitro and in vivo experiments.
. Alamgeer, Qurat ul Ain, Umme Habiba Hasan, Hira Asif   +3 more
doaj   +1 more source

Clinical Significance of Prothrombin Time in Cholangiocarcinoma Patients with Surgeries

Canadian Journal of Gastroenterology and Hepatology, 2019
Background. Prothrombin time (PT) can predict survival in several types of malignancies. This study aims to investigate the predictive values of PT levels in patients with cholangiocarcinoma (CCA). Methods.
Hui-shan Wang, Xian-xiu Ge, Quan-peng Li, Jun-jie Nie, Lin Miao   +4 more
doaj   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo, Liumbruno, Giancarlo Maria, Marano, Giuseppe, Mengoli, Carlo, Piccinini, Vanessa, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Nomogram for predicting bleeding events in nonvalvular atrial fibrillation patients receiving rivaroxaban: A retrospective study

Health Science Reports
Background and Aims To construct a bleeding events prediction model of nonvalvular atrial fibrillation (NVAF) patients receiving rivaroxaban. Methods We conducted a retrospective cohort study in patients with NVAF who received rivaroxaban from June 2017 ...
Chang Cao, Yijiao Xu, Weiwen Jiang, Shujing Wu, Yun Shen, Xiaotong Xia, Lumin Wang, Huijun Zhang, Hongni Jiang, Xiaoyu Li, Xiaoye Li, Yanrong Ye   +11 more
doaj   +1 more source

Coagulation Profile in Type 2 Diabetes Mellitus and its Association with Glycaemic Control and Long-term Complications: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Diabetes Mellitus (DM) causes numerous complications due to the formation of Advanced Glycation End-products (AGEs) in the presence of persistent hyperglycaemia.
Anindita Banerjee, Gargi Mukherjee, Ayan Kundu, Debarshi Saha   +3 more
doaj   +1 more source

A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]

, 2002
The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Gaffney, P.J., Howarth, D., Kitchen, S., Lawrie, A.S., Lowe, G.D.O., Mackie, I.J., Martin, J., Purdy, G., Rigsby, P., Rumley, A.   +9 more
core   +1 more source

Prescription trends for combined oral contraceptives and thromboembolism incidence in Japan before and after public awareness events in 2013–2015

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Combined oral contraceptives (COCs) for dysmenorrhea management have been covered by the Japanese universal health insurance system since 2008. Several public awareness events regarding COC prescriptions for dysmenorrhea were implemented between 2013 and 2015, including media reports on COC‐related fatalities in 2013, drug safety ...
Risa Ishida, Yusuke Sasabuchi, Kaori Koga, Shiori Itoi, Gentaro Izumi, Daisuke Shigemi, Hiroki Matsui, Yutaka Osuga, Hideo Yasunaga   +8 more
wiley   +1 more source

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR, Chu, K, Golden, JA, Herzog, RW, High, KA, Labosky, PA, Margaritis, P, Tai, SJ   +7 more
core   +2 more sources

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source