Results 91 to 100 of about 14,526,235 (284)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Factor IX and thrombosis [PDF]

, 2001
No abstract ...
Lowe, G.D.O.
core   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

iNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen, Qifei Guan, Yufeng Gao, Zhenhua Zhang, Hongchuan Zhao, Beicheng Sun   +5 more
wiley   +1 more source

A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs)

Upsala Journal of Medical Sciences, 2017
Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC procedure: Zafena’s Simple Simon™ PT-INR, a room-temperature, wet-chemistry prothrombin time method of
Tomas L. Lindahl, Kerstin Arbring, Maria Wallstedt, Mats Rånby   +3 more
doaj   +1 more source

Establishment of Reference Intervals for Thrombus Biomarkers in a Single‐Center Chinese Population Using Indirect Methods

Journal of Clinical Laboratory Analysis, EarlyView.
This study established and validated comprehensive RIs for four key thrombus biomarkers (TAT, PIC, TM, and t‐PAIC) in a Chinese population using the Hoffmann and Bhattacharya indirect methods on a large clinical dataset. The tailored RIs offer a practical tool for early detection and risk assessment of thrombotic diseases, supporting more precise and ...
Lei Zhang, Qiyu Hu, Yiming Chen, Hui Yuan   +3 more
wiley   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen, Yi Yao, Bing Zhao, Yuan An, Jian Jiang, Li Ma, Enqiang Mao, Yihui Wang   +7 more
wiley   +1 more source

Hospital Volume and Operative Mortality in Pancreaticoduodenectomy and Hepatectomy: Analysis of the National Clinical Database in Japan

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose This study evaluated the association between institutional advanced hepatobiliary‐pancreatic (HBP) surgical volume and operative mortality for pancreaticoduodenectomy (PD) and advanced hepatectomy using data from the Japanese National Clinical Database.
Yoshitaro Shindo, Hideki Endo, Hiroyuki Yamamoto, Hidenori Takahashi, Shigeru Marubashi, Atsushi Nanashima, Itaru Endo, Hideki Ueno, Ken Shirabe, Masafumi Nakamura, Hiroaki Nagano, Masayuki Ohtsuka   +11 more
wiley   +1 more source

Interpretation of Prothrombin Time and Activated Partial Thromboplastin Time Mixing Studies Using Predefined Algorithms

Clinical and Applied Thrombosis/Hemostasis
Background Mixing test plasma with prolonged Prothrombin Time (PT) and activated partial thromboplastin time (aPTT) with normal plasma in a 1:1 ratio, helps distinguish between clotting factor deficiency and inhibitors.
Fatima Farhan, Bushra Afaq Rizvi, Bushra Moiz   +2 more
doaj   +1 more source

Prevalence and clinical associations of prolonged prothrombin time in adult untreated coeliac disease.

, 2004
Introduction Untreated coeliac disease may induce malabsorption of many nutrients. It may also induce vitamin K deficiency, which causes prolongation of the prothrombin time.
R. TORTORA, A. PALUMBO, F. SABBATINI, IOVINO, Paola, R. CAVALLARO, G. MAZZACCA, S. DIBELLA, F. LABANCA, F. CASTIGLIONE, S. DI BELLA, CIACCI, Carolina, CASTIGLIONE, FABIANA, M. MARINO, C. CIACCI   +13 more
core   +1 more source

The Clinicopathological Characteristics and Prognosis of Cholangiolocarcinoma: A Multicenter Study With a Central Pathology Review

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Cholangiolocarcinoma (CLC) is a rare liver cancer with ≥ 80% ductular configuration (DC). Given its rarity, its clinicopathological characteristics remain poorly understood, and its status as a distinct disease entity remains controversial.
Takamichi Ishii, Kenta Makino, Etsuro Hatano, Mina Komuta, Jun Akiba, Yoshihiro Sakamoto, Shun‐Ichi Ariizumi, Goro Honda, Toru Hisaka, Yutaka Takeda, Akira Shimizu, Kentaro Yasuchika, Takashi Mizuno, Daisuke Asano, Atsushi Fujio, Naoto Gotohda, Chie Kitami, Koji Amaya, Hiroshi Sadamori, Manabu Kawai, Akiyoshi Nakakura, Masafumi Nakamura, Itaru Endo   +22 more
wiley   +1 more source