Results 21 to 30 of about 17,100,037 (350)

Perbedaan Pengaruh Pemberian Infus HES Dengan Berat Molekul 40 kD dan 200 kD Terhadap Plasma Prothrombin Time dan Partial Thromboplastin Time Kajian Pada Pasien Dengan Perdarahan Sampai 20% Estimated Blood Volume

JAI (Jurnal Anestesiologi Indonesia), 2009
Latar belakang: Pasien dengan operasi besar yang beresiko terjadi perdarahan semakin meningkat setiap tahun. HES dengan berat molekul besar mempertahankan hemodinamik lebih baik tetapi mengganggu faktor koagulasi.
Hari Hendriarto Satoto, Ery Leksana, Uripno Budiono   +2 more
doaj   +1 more source

Are prothrombin time and clot waveform analysis useful in detecting a bleeding risk in liver cirrhosis?

International Journal of Laboratory Hematology, 2018
Prothrombin time is thought to be unreliable in cirrhotic patients to predict the risk of bleeding. We investigated whether prothrombin time ratio was an independent risk factor for bleeding alongside its clot waveform analysis.
M. Ruberto, F. Marongiu, O. Sorbello, A. Civolani, L. Demelia, D. Barcellona   +5 more
semanticscholar   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Evaluating the analytical performance of five new coagulation assays for the measurement of prothrombin time and activated thromboplastin time

International Journal of Laboratory Hematology, 2018
New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT).
S. Kitchen, U. Geisen, J. Kappelmayer, P. Quehenberger, J. Driess, Anna Lowe, Robert Jones, Jana G. Boehm, G. Miles, Gergely Rozsnyai   +9 more
semanticscholar   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

Effect of Hypoxic Ischaemic Encephalopathy on Coagulation Profile in Neonates in a Tertiary Care Center, Agra- A Prospective Clinical Study

Indian Journal of Neonatal Medicine and Research, 2023
Introduction: Perinatal asphyxia is very common in developing countries. Coagulopathy occurs as a part of spectrum of multiorgan dysfunction following hypoxic insult.
Payal Mittal, Shehraz Firoz, Digvijay Ghangas, Sonia Bhatt   +3 more
doaj   +1 more source

A retrospective discussion of the prognostic value of combining prothrombin time(PT) and fibrinogen(Fbg) in patients with Hepatocellular carcinoma

Journal of Cancer, 2017
Aims: The levels of coagulation system tests have been studied in various cancers. In this study, our aim is to evaluate the prognostic value of pretreatment plasma coagulation tests in hepatocellular carcinoma (HCC) patients.
Xue-ping Wang, M. Mao, Zhonglian He, Lin Zhang, P. Chi, J. Su, Shuqin Dai, Wan-li Liu   +7 more
semanticscholar   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Clinical evaluation of whole blood prothrombin time (PT) and international normalized ratio (INR) using a Laser Speckle Rheology sensor

Scientific Reports, 2017
Prothrombin time (PT) and the associated international normalized ratio (INR) are routinely tested to assess the risk of bleeding or thrombosis and to monitor response to anticoagulant therapy in patients.
Markandey M. Tripathi, Satoru Egawa, A. Wirth, D. Tshikudi, E. V. Van Cott, S. Nadkarni   +5 more
semanticscholar   +1 more source

A Combined Pharmacometrics Analysis of Biomarker Distribution Under Treatment With Standard- or Low-Dose Rivaroxaban in Real-World Chinese Patients With Nonvalvular Atrial Fibrillation

Frontiers in Pharmacology, 2022
Background: The rivaroxaban dose regimen for patients with nonvalvular atrial fibrillation (NVAF) is complex in Asia. Given the high interindividual variability and the risk of bleeding caused by rivaroxaban in Asians, the influencing factors and the ...
Nan Zhao, Nan Zhao, Zhiyan Liu, Qiufen Xie, Zhe Wang, Zhe Wang, Zhongyi Sun, Qian Xiang, Yimin Cui, Yimin Cui, Yimin Cui   +10 more
doaj   +1 more source