Results 21 to 30 of about 17,468,048 (391)

Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis [PDF]

open access: yes, 2002
Hormone replacement therapy (HRT) increases the risk of venous thrombosis. We investigated whether this risk is affected by carriership of hereditary prothrombotic abnormalities.
A. Rumley   +26 more
core   +1 more source

Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant\ue2\u80\u93anticoagulant equilibrium toward thrombosis [PDF]

open access: yes, 2017
Blood coagulation is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion of the prothrombin (ProT) zymogen to active -thrombin (T).
Acquasaliente, Laura   +5 more
core   +1 more source

Biological variation estimates of prothrombin time, activated partial thromboplastin time, and fibrinogen in 28 healthy individuals

open access: greenInternational Journal of Laboratory Hematology, 2018
Although tests of global hemostasis prothrombin time (PT) and activated partial thromboplastin time (aPTT) should not be used for prediction of bleeding risk, these tests are often used by many clinicians in daily practice particularly as a preoperative ...
Mesude Falay   +7 more
openalex   +3 more sources

How we treat bleeding associated with direct oral anticoagulants [PDF]

open access: yes, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo   +4 more
core   +1 more source

Perbedaan Pengaruh Pemberian Infus HES Dengan Berat Molekul 40 kD dan 200 kD Terhadap Plasma Prothrombin Time dan Partial Thromboplastin Time Kajian Pada Pasien Dengan Perdarahan Sampai 20% Estimated Blood Volume

open access: yesJAI (Jurnal Anestesiologi Indonesia), 2009
Latar belakang: Pasien dengan operasi besar yang beresiko terjadi perdarahan semakin meningkat setiap tahun. HES dengan berat molekul besar mempertahankan hemodinamik lebih baik tetapi mengganggu faktor koagulasi.
Hari Hendriarto Satoto   +2 more
doaj   +1 more source

Pediatric liver transplantation from neonatal donors [PDF]

open access: yes, 1992
Sixteen recipients of neonatal liver grafts were compared with 114 contemporaneous pediatric recipients of grafts from older donors. Graft and patient survival were worse in the neonatal group although the differences were not statistically significant ...
Bismuth H   +9 more
core   +1 more source

Evaluating the analytical performance of five new coagulation assays for the measurement of prothrombin time and activated thromboplastin time

open access: yesInternational Journal of Laboratory Hematology, 2018
New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT).
S. Kitchen   +9 more
semanticscholar   +1 more source

Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]

open access: yes, 2010
The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Braun, Jean-Pierre   +5 more
core   +1 more source

Are prothrombin time and clot waveform analysis useful in detecting a bleeding risk in liver cirrhosis?

open access: yesInternational Journal of Laboratory Hematology, 2018
Prothrombin time is thought to be unreliable in cirrhotic patients to predict the risk of bleeding. We investigated whether prothrombin time ratio was an independent risk factor for bleeding alongside its clot waveform analysis.
M. Ruberto   +5 more
semanticscholar   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

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