Results 311 to 320 of about 17,468,048 (391)

Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis

open access: yesThe FASEB Journal, Volume 39, Issue 23, 15 December 2025.
The coagulation and complement cascades were elevated in the pathogenesis of chronic kidney disease (CKD) and may contribute to both kidney injury and cardiovascular risk. These excessive signals and the associated innate immune responses were suppressed by the NAD+ precursor nicotinamide (NAM).
Saori Kin   +6 more
wiley   +1 more source

Insulin, glucagon, peptide and amino acid levels following liver transplantation [PDF]

open access: yes, 1987
Conte, D   +9 more
core  

NQO1/p65/CXCL12 Axis‐Recruited Tregs Mediate Resistance to Anti‐PD‐1 Plus Lenvatinib Therapy in PIVKA‐II‐Positive Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
High PIVKA‐II expression in HCC correlates with resistance to anti‐PD‐1 plus lenvatinib, driven by an immunosuppressive TME. NQO1/p65/CXCL12 axis recruits Tregs to promote resistance to anti‐PD‐1 plus lenvatinib in HCC with high PIVKA‐II expression.
Biao Gao   +18 more
wiley   +1 more source

Identification of Six Potential Therapeutic Targets Common to Ischemic Stroke and Vascular Dementia: Genetic Insights From an Integrated Bioinformatics Analysis

open access: yesBrain and Behavior, Volume 15, Issue 12, December 2025.
This graphical abstract summarizes a multi‐layered analytical framework integrating cis‐eQTLs, UKB‐PPP proteomics, and multivariable Mendelian randomization to dissect the causal links between circulating proteins, vascular risk factors, ischemic stroke (IS), and vascular dementia (VD).
Jian Lyu   +9 more
wiley   +1 more source

Comparative Analysis of Fecal Microbiota in Healthy Controls and Pancreatic Cancer Patients: A Focus on Tumor Localization Differences in Pancreatic Head and Body–Tail

open access: yesCancer Medicine, Volume 14, Issue 24, December 2025.
ABSTRACT Background Pancreatic cancer (PC) remains one of the most lethal malignancies worldwide, characterized by late‐stage diagnosis and a poor prognosis. This study explores the clinical, biochemical, and gut microbiota differences between PC patients and healthy controls (CTRL), as well as between subgroups of PC patients with pancreatic head ...
Annacandida Villani   +10 more
wiley   +1 more source

Comparison of in‐Hospital Complication Rates After Transcatheter Aortic Valve Replacement in Patients With Bicuspid Versus Tricuspid Aortic Valves: A Retrospective Cohort Study

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 7, Page 3489-3497, December 1, 2025.
ABSTRACT Background Transcatheter aortic valve replacement (TAVR) has become a popular alternative to surgical aortic valve replacement (SAVR) for patients with valvular heart disease (VHD), particularly for those with aortic anomalies. Aims The study aimed to compare the risks of post‐TAVR complications between patients with bicuspid and tricuspid ...
Tingxi Zhu   +8 more
wiley   +1 more source

Left Ventricular Apical Thrombus in Apical Hypertrophic Cardiomyopathy Without Aneurysm or Arrhythmia: A Case Report

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 7, Page 3649-3652, December 1, 2025.
ABSTRACT Apical hypertrophic cardiomyopathy (ApHCM) is a rare variant of hypertrophic cardiomyopathy, typically associated with a benign course. However, complications such as ventricular arrhythmias, apical aneurysms, and thrombus formation may occur. Left ventricular (LV) thrombus is an unusual finding in ApHCM, especially in patients with preserved ...
Ibrahim Antoun   +2 more
wiley   +1 more source

Prothrombin Time

Transfusion Medicine and Hemostasis, 2019
Mikhail Roshal, Morayma Reyes Gil
openaire   +2 more sources

ESTIMATION OF PROTHROMBIN TIME

Journal of the American Medical Association, 1948
To the Editor:— The opinion grows that the results of estimation of prothrombin time should be reported in terms of per cent or of per cent of normal. Recently, a plea has been made that the practice be made universal (Allen, E. V.:The Journal, page 323, May 24, 1947).
S, SHAPIRO, M, WEINER
openaire   +2 more sources

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