Modified application of SAMe-TTR scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants [PDF]
Background/Aims The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those ...
Seong Won Jeon+7 more
doaj +1 more source
ABSTRACT Background COVID‐19 can affect hematological and biochemical parameters, potentially altering platelet function. This study aimed to evaluate the long‐term effects of COVID‐19 on the quality of platelet concentrates (PCs) collected from donors with a history of infection.
Fatemeh Arastehnazar+4 more
wiley +1 more source
A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs)
Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC procedure: Zafena’s Simple Simon™ PT-INR, a room-temperature, wet-chemistry prothrombin time method of
Tomas L. Lindahl+3 more
doaj +1 more source
Clinical Utilisation of Cryoprecipitate at a Tertiary Care Centre in Telangana, India: A Quasi-experimental Study [PDF]
Introduction: Cryoprecipitate is a slushy product derived from Fresh Frozen Plasma (FFP) through centrifugation at specific temperatures and speeds. It is rich in factor VIII or antihaemorrhagic factor, fibrinogen, and minor amounts of other clotting ...
Sudhir Kumar Vujhini+3 more
doaj +1 more source
Persistent AST Elevation in a Patient With Ovarian Cancer: A Rare Diagnostic Challenge
ABSTRACT Background Persistent elevation of aspartate aminotransferase (AST) is commonly indicative of liver injury or disease, but isolated AST elevation without concurrent alanine aminotransferase (ALT) increase is rare and difficult to diagnose. While AST is non‐specific and found in various tissues, its isolated elevation is due to less common ...
Lechuang Chen, Yu Zhang, Qing H. Meng
wiley +1 more source
COMPARATIVE VALUE OF BROMSULPHALEIN, SERUM PHOSPHATASE, PROTHROMBIN TIME, AND INTRAVENOUS GALACTOSE TOLERANCE TESTS IN DETECTING HEPATIC DAMAGE PRODUCED BY CARBON TETRACHLORIDE [PDF]
Victor A. Drill, A. C. Ivy
openalex +1 more source
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez+8 more
wiley +1 more source
The correlations of right coronary artery (RCA) diameter with gallbladder (GB) width and GB distension with the development of coronary arteries anomalies have already been described.
L. M. Strilchuk+4 more
doaj +1 more source
The Action of p-Aminosalicylic Acid on Prothrombin Time in Man [PDF]
A. L. Tárnoky, L. Steingold
openalex +1 more source
Pharmacokinetics and Safety of Fezolinetant in Women with Hepatic or Renal Impairment
Abstract The neurokinin 3 receptor antagonist fezolinetant is an approved treatment for vasomotor symptoms due to menopause. The impacts of hepatic and renal impairment on the pharmacokinetics and safety of a single oral dose of fezolinetant 30 mg were investigated in two independent studies.
Megumi Iwai+8 more
wiley +1 more source