Results 71 to 80 of about 17,401,114 (355)

The compound heterozygous mutations of c.607G>a and c.657delC in the FAH gene are associated with renal damage with hereditary tyrosinemia type 1 (HT1)

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
This study demonstrated the novel compound heterozygous mutations (NM_000137: c.657delC (p.K220Rfs*12) and NM_000137: c.607G>A(p.A203T)) in FAH gene in a patient were responsible for HT1. We showed these FAH mutations were inherited in an autosomal recessive manner and resulted in abnormal FAH protein expression and dysfunction, leading to ...
Huan Chi, Chun Gan, Yaru Jiang, Dan Chen, Jiawen Qiu, Qing Yang, Yaxi Chen, Mo Wang, Haiping Yang, Wei Jiang, Qiu Li   +10 more
wiley   +1 more source

Successful conservative management of pathological mandibular fracture resulting from chronic osteomyelitis in a 90‐year‐old woman

Oral Science International, Volume 20, Issue 1, Page 42-47, January 2023., 2023
Abstract Background We report the successful conservative management of a pathological mandibular fracture resulting from chronic osteomyelitis in a super‐elderly patient. Case Presentation A 90‐year‐old woman was admitted because of an external dental fistula with purulent drainage. Radiographs showed extensive bone destruction in the mandible.
Ryutaro Ono, Takeshi Amemiya, Toshiro Yamamoto, Narisato Kanamura   +3 more
wiley   +1 more source

Effects of Verapamil and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Rivaroxaban

Pharmaceutics, 2019
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-
Minsoo Kim, Heebin Son, Keumhan Noh, Eunyoung Kim, Beom Soo Shin, Wonku Kang   +5 more
doaj   +1 more source

Hemostatic activities of methanol leaf extracts of Croton megalocarpus Hutch and Lantana camara Linn

Journal of Advanced Biotechnology and Experimental Therapeutics, 2021
Hemostasis is the natural mechanism by which blood is kept in a fluid state in circulation with the ability to cause clotting at an injury site. The effects of Croton megalocarpus Hutch and Lantana camara Linn plants leaves on blood coagulation has not ...
Hezron Mutisya Muindi, Cromwell Mwiti Kibiti, Mathew Piero Ngugi   +2 more
doaj   +1 more source

Updated risk prediction model for pancreaticoduodenectomy using data from the National Clinical Database in Japan

Annals of Gastroenterological Surgery, EarlyView.
The calibration plots of the updated risk models for the endpoints were analyzed in each cohort. The predicted probability of each endpoint matched the observed probability in the development and validation cohorts. Abstract Aim Risk prediction models for mortality, severe postoperative complications, and postoperative pancreatic fistula in patients ...
Masamichi Mizuma, Hideki Endo, Hiroyuki Yamamoto, Mitsuhiro Shimura, Masahiro Iseki, Michiaki Unno, Taro Oshikiri, Yoshihiro Kakeji, Ken Shirabe   +8 more
wiley   +1 more source

Effects of an increase in emergency cases with difficulties in transport to hospital during the COVID‐19 pandemic on postoperative short‐term outcomes of colorectal perforation: A study based on the National Clinical Database

Annals of Gastroenterological Surgery, EarlyView.
In 2022, emergency cases with difficulties in transport markedly increased during the COVID‐19 pandemic, but had little effect on short‐term outcomes of colorectal perforation. These data suggest that the emergency system for patients with colorectal perforation was largely maintained during the pandemic in Japan, with no evidence indicating a serious ...
Shimpei Ogawa, Hideki Endo, Masahiro Yoshida, Tomomitsu Tsuru, Michio Itabashi, Hiroyuki Yamamoto, Yoshihiro Kakeji, Hideki Ueno, Ken Shirabe, Taizo Hibi, Akinobu Taketomi, Norihiko Ikeda, Masaki Mori   +12 more
wiley   +1 more source

STANDARDIZATION OF PROTHROMBIN TIME TEST AND EVALUATION OF QUALITY OF PATIENT MANAGEMENT WITH WARFARIN

Journal of Research in Medical Sciences, 2000
Background. The most common mode of monitoring anticoagulation therapy is the use of prothrombin time (PT). There exist several methods for reporting results of PT. These include prothrombin time in seconds, prothrombin activity percent, prothrombin time
A.H ZARGARZADEH, A.A POURAZAR, M MORABI
doaj  

Quick or Owren prothrombin time methods: possibilities and limitations (literature review)

Медицина неотложных состояний
Background. To treat patients with hypocoagulation, an objective assessment of the hemostasis system is mandatory. Owren prothrombin time method is rare in Ukrainian hospitals.
R.A. Zatsarynnyi, O.Yu. Khomenko, Y.A. Stadnik, K.S. Smirnova, J. Ptasekas   +4 more
doaj   +1 more source

Oral contraceptives and the prothrombin time. [PDF]

BMJ, 1980
PIP: Dr. De Teresa and others reported that mean prothrombin time ratio of 12 patients on long-term anticoagulation with warfarin was significantly higher when they were also taking oral contraceptives (OCs). A study of prothrombin complex activity was recently conducted in female rats treated with an estrogen-progestogen combination (lynestrenol 5 mg;
Maria Benedetta Donati, Maria Carla Roncaglioni, J Pangrazzi   +2 more
openaire   +2 more sources

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka, Masahiro Ohira, Tsuyoshi Kobayashi, Naruhiko Honmyo, Michinori Hamaoka, Takashi Onoe, Daisuke Takei, Koichi Oishi, Tomoyuki Abe, Toshihiro Nakayama, Miho Akabane, Kazunari Sasaki, Hideki Ohdan, Hiroshima Surgical study group of Clinical Oncology (HiSCO)   +13 more
wiley   +1 more source