Results 71 to 80 of about 92,349 (287)

Modified application of SAMe-TTR scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants [PDF]

open access: yesThe Korean Journal of Internal Medicine
Background/Aims The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those ...
Seong Won Jeon   +7 more
doaj   +1 more source

Evaluation of Function and Biochemical Parameters of Platelet Concentrates (PCs) Prepared From Blood Donors With a History of COVID‐19 During the Platelet Storage

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background COVID‐19 can affect hematological and biochemical parameters, potentially altering platelet function. This study aimed to evaluate the long‐term effects of COVID‐19 on the quality of platelet concentrates (PCs) collected from donors with a history of infection.
Fatemeh Arastehnazar   +4 more
wiley   +1 more source

A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs)

open access: yesUpsala Journal of Medical Sciences, 2017
Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC procedure: Zafena’s Simple Simon™ PT-INR, a room-temperature, wet-chemistry prothrombin time method of
Tomas L. Lindahl   +3 more
doaj   +1 more source

Clinical Utilisation of Cryoprecipitate at a Tertiary Care Centre in Telangana, India: A Quasi-experimental Study [PDF]

open access: yesNational Journal of Laboratory Medicine
Introduction: Cryoprecipitate is a slushy product derived from Fresh Frozen Plasma (FFP) through centrifugation at specific temperatures and speeds. It is rich in factor VIII or antihaemorrhagic factor, fibrinogen, and minor amounts of other clotting ...
Sudhir Kumar Vujhini   +3 more
doaj   +1 more source

Persistent AST Elevation in a Patient With Ovarian Cancer: A Rare Diagnostic Challenge

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Persistent elevation of aspartate aminotransferase (AST) is commonly indicative of liver injury or disease, but isolated AST elevation without concurrent alanine aminotransferase (ALT) increase is rare and difficult to diagnose. While AST is non‐specific and found in various tissues, its isolated elevation is due to less common ...
Lechuang Chen, Yu Zhang, Qing H. Meng
wiley   +1 more source

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

Laboratory and instrumental parameters of patients with ischemic heart disease in dependence of gallbladder condition: correlational analysis

open access: yesZaporožskij Medicinskij Žurnal, 2017
The correlations of right coronary artery (RCA) diameter with gallbladder (GB) width and GB distension with the development of coronary arteries anomalies have already been described.
L. M. Strilchuk   +4 more
doaj   +1 more source

Pharmacokinetics and Safety of Fezolinetant in Women with Hepatic or Renal Impairment

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract The neurokinin 3 receptor antagonist fezolinetant is an approved treatment for vasomotor symptoms due to menopause. The impacts of hepatic and renal impairment on the pharmacokinetics and safety of a single oral dose of fezolinetant 30 mg were investigated in two independent studies.
Megumi Iwai   +8 more
wiley   +1 more source

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