ProtoPred: Advancing Oncological Research Through Identification of Proto-Oncogene Proteins [PDF]
IEEE Access, 2021 Proto-oncogenes are the genes that have the potential to transform normal cells into cancer cells as a result of mutations. They usually contain encoding of proteins whose function is to inhibit cell differentiation, stimulate cell division, and prevent ...
Sharaf J. Malebary +2 more
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Human proto-oncogene N-myc encodes nuclear proteins that bind DNA [PDF]
Molecular and Cellular Biology, 1986 N-myc is a gene whose amplification has been implicated in the genesis of several malignant human tumors. We have identified two proteins with molecular weights of 65,000 and 67,000 encoded by N-myc. The abundance of these proteins in tumor cells was consonant with the extent of amplification of N-myc.
G. Ramsay +3 more
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Interplay of the Proto-oncogene Proteins CrkL and CrkII in Insulin-like Growth Factor-I Receptor-mediated Signal Transduction [PDF]
Journal of Biological Chemistry, 1998 The closely related proto-oncogene proteins CrkII and CrkL consist of one SH2 and two SH3 domains and share 60% overall homology with the highest identity within their functional domains. In this study we show that CrkL and CrkII may play overlapping but
Anatoliy Koval +3 more
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The protein encoded by the human proto-oncogene c-myc. [PDF]
Proceedings of the National Academy of Sciences, 1984 The proto-oncogene c-myc may play a role in controlling the growth and division of normal cells, and abnormalities of the gene have been implicated in the genesis of a substantial variety of human tumors. To facilitate further study of these issues, we developed antisera that permit the identification and isolation of the protein encoded by the human ...
Gary Ramsay, G. Evan, J. Bishop
semanticscholar +3 more sources
Transcriptional regulation of 1-cys peroxiredoxin by the proto-oncogene protein DEK
Molecular Medicine Reports, 2010 The nuclear phosphoprotein DEK is abundantly present in cells and is implicated in diseases including leukemia and autoimmune disorders. DEK has three highly acidic amino acid domains and inhibits histone acetyltransferase activity by binding directly to histones.
Seo
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Ret proto-oncogene (RET); KIF5B-RET oncogenic fusion protein [PDF]
Science-Business eXchange, 2013 openalex +2 more sources
Phosphorylated Proto-Oncogene Tyrosine-Protein Kinase Src [PDF]
, 2020 National Cancer Institute
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Proto-Oncogene Tyrosine-Protein Kinase Src [PDF]
, 2020 National Cancer Institute
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Immunohistochemistry in Anaplastic Lymphoma Kinase and Proto-Oncogene Tyrosine-Protein Kinase ROS [PDF]
Archives of Pathology & Laboratory Medicine, 2018 Mari Mino–Kenudson
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Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in primary and recurrent colorectal cancers [PDF]
Kosin Medical Journal, 2022 Background Colorectal cancer is one of the most common cancers worldwide. Colorectal cancer that has recurred and metastasized to other organs also has a very poor prognosis.
Kyung-Yoon Jeon +6 more
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