Results 71 to 80 of about 348,341 (313)
Identification of the product of two oncogenic rearranged forms of the RET proto-oncogene in papillary thyroid carcinomas. [PDF]
, 1992 In papillary thyroid carcinomas, we have identified two tumor-specific rearrangements of the RET proto-oncogene leading to the formation of different transforming fusion products sharing the tyrosine kinase (tk) domain of the proto-oncogene and ...
M. Grieco +9 more
core +2 more sources
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015 Background and Objectives: Exposure to cadmium in early pregnancy has long-term effects on the growth and function of the liver. One of the pathways that controls proliferation of the fetal liver involves hepatocyte growth factor (HGF).
Hossein Ali Asgharzade Oliaei +2 more
doaj
Cancer Medicine, 2023 Background Activating mutations of the KRAS occurs in >90% of pancreatic ductal adenocarcinoma (PDAC) cases. However, direct pharmacological targeting of the activated KRAS protein has been challenging.
Akiko Tsujimoto +10 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The N-terminal region of proto-dbl down regulates its transforming activity [PDF]
, 1989 The dbl proto-oncogene can transform NIH3T3 cells when overexpressed, but its transforming activity is about 50 to 70 fold lower than that of the dbl oncogene. The dbl oncogene encodes a protein of 478 amino-acids while proto-dbl encodes a protein of 925
Ron, D +5 more
core
Effects of ras and other proto-oncogenes on autoimmunity [PDF]
, 2022 Control and regulation of cell growth, development, and reproductive functions are provided by proteins encoded by proto-oncogene and tumor suppressor genes.
Şahin, Mehtap
core
Sperm-Egg Binding Protein or Proto-Oncogene? [PDF]
Science, 1996 J Y, Tsai, L M, Silver
openaire +5 more sources
Risk factors analysis for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma [PDF]
精准医学杂志Objective To investigate the risk factors for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma (IF-PTC). Methods A total of 134 patients with IF-PTC who underwent surgical treatment in our hospital from August
LI Lei, ZHAN Jiezhi, LI Hui, WANG Ruiqing, ZHAO Cheng
doaj +1 more source
Identification and characterization of the protein encoded by the human c‐myb proto‐oncogene. [PDF]
The EMBO Journal, 1986 We have identified the product of the human c-myb proto-oncogene as a 80,000-Mr protein, p80c-myb, by using polyclonal and monoclonal antibodies raised against a bacterially synthesized polypeptide from the amino terminus of the viral myb protein. p80c-myb shares at least two distinct antigenic sites with the amino terminal region of the v-myb protein.
K H, Klempnauer, C, Bonifer, A E, Sippel
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source