Results 61 to 70 of about 23,181 (145)
Protein token: a dynamic unit in protein interactions [PDF]
In this study, we introduced a new unit, named "protein token", as a dynamic protein structural unit for protein-protein interactions. Unlike the conventional structural units, protein token is not based on the sequential or spatial arrangement of residues, but comprises remote residues involved in cooperative conformational changes during protein ...
arxiv
This study demonstrates that high‐intensity interval training (HIIT) effectively alleviates OA‐induced inflammation by promoting M1 to M2 microglial polarisation via the Jak2/Stat3 pathway. HIIT increases pain thresholds and down‐regulates the expression of pro‐inflammatory factors such as Tmem119, SP, Glu, c‐Fos, and IL‐6 in an OA rat model.
Xinwei Wang+5 more
wiley +1 more source
Differential gene expression in the recovery from ischemic renal injury [PDF]
Differential gene expression in the recovery from ischemic renal injury. Recovery from renal ischemia requires regeneration of damaged tubular epithelium. Previous studies have examined the expression of proto-oncogenes and growth factors after ischemia,
Paller, Mark S., Rosenberg, Mark E.
core +1 more source
Protein kinase C regulates proliferation of mast cells and the expression of the mRNAs of fos and jun proto-oncogenes during activation by IgE-Ag or calcium ionophore A23187 [PDF]
D Baranes, E Razin
openalex +3 more sources
Refining the Protein-Protein Interactome using Gene Expression Data [PDF]
Proteins interact with other proteins within biological pathways, forming connected subgraphs in the protein-protein interactome (PPI). Proteins are often involved in multiple biological pathways which complicates interpretation of interactions between proteins.
arxiv
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong+5 more
wiley +1 more source
Advances in the Study of Metabolic Reprogramming in Gastric Cancer
ABSTRACT Background Gastric cancer is one of the most prevalent malignancies of the digestive system and is associated with a poor prognosis, particularly in advanced metastatic stages, where the 5‐year survival rate is significantly low. Methods Recent research has demonstrated that metabolic reprogramming—including alterations in glucose, lipid, and ...
Yu Rong, Yuanyin Teng, Xiaoying Zhou
wiley +1 more source
Global protein function prediction in protein-protein interaction networks [PDF]
The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of single proteins or small complexes to that of the entire proteome. In this context, the search for reliable methods
arxiv
ABSTRACT Background Globally, infections account for 10% of new cancer cases, and cancer can compromise the immune system, increasing the risk of infections. With advances in cancer treatment, widespread use of immunotherapy, and prolonged survival of cancer patients, the coexistence of tuberculosis (TB) and cancer is becoming increasingly common in ...
Wendi Zhou+7 more
wiley +1 more source
Translational Regulation of the C-Jun Proto-Oncogene [PDF]
The v-jun oncogene was originally isolated from the ASV17 virus in 1987. Ever since its isolation, extensive work has been done to understand the role of the v-jun oncogene in cell transformation.
Sehgal, Anil
core +1 more source