Results 131 to 140 of about 75,334 (151)

Construction of a circRNA-miRNA-mRNA regulatory network in glioblastoma multiforme based on bioinformatics analysis. [PDF]

Medicine (Baltimore)
Hu D, Chen K.
europepmc   +1 more source

Omics Insights into Cylindrospermopsin's Molecular Toxicity. [PDF]

Foods
Borja RF, Plata-Calzado C, Diez-Quijada L, Puerto M.   +3 more
europepmc   +1 more source

Decoding Chronicity: Oxidative Stress and Inflammation as Systems Hubs. [PDF]

Biomedicines
Formanowicz D.
europepmc   +1 more source

Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation.

Alcohol and alcoholism (Oxford, Oxfordshire), 1994
Hepatic fibrosis is an important morphological feature of alcohol-induced liver injury. We previously reported that acetaldehyde stimulates collagen I and fibronectin gene transcription in rat fat-storing cell (FSC) culture. We here evaluated whether acetaldehyde increases Col I and FN gene transcription through the induction of c-fos and c-jun proto ...
CASINI, ALESSANDRO, GALLI, GIANNA, R. SALZANO, CENI, ELISABETTA, F. FRANCESCHELLI, ROTELLA, CARLO MARIA, SURRENTI, CALOGERO   +6 more
  +6 more sources

Differential expression of the c-jun proto oncogene during the cellular response to ionizing radiation is deminished by protein kinase C inhibitors

International Journal of Radiation Oncology*Biology*Physics, 1990
of DNA dsb were, therefore, studied in the above cell lines using a pulse field gel electrophoresis technique, the asymetric field inversion gel electrophoresis (AFIGE). Small variations were observed in the induction and repair of DNA dsb in these two cell lines that could be largely explained by differences in the distribution of cells in the various
D.E. Hallahan, M.L. Sherman, M.A. Beckett, S. Virudachalam, D. Kufe, R.R. Weichselbaum   +5 more
openaire   +2 more sources

Induction of the c-jun proto-oncogene by a protein kinase c-dependent mechanism during exposure of human epidermal keratinocytes to ethanol

Biochemical Pharmacology, 1993
The present work demonstrates that ethanol induces expression of the c-jun proto-oncogene in human keratinocytes. Increased c-jun mRNA levels were detectable at 1 hr of exposure to 1% ethanol and at 24 hr remained above that in control keratinocytes. An increase in c-jun expression was also detectable at ethanol concentrations of 0.1 and 0.5%.
S, Kharbanda, T, Nakamura, D, Kufe
openaire   +3 more sources

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

Science, 1987
Nuclear oncogene products have the potential to induce alterations in gene regulation leading to the genesis of cancer. The biochemical mechanisms by which nuclear oncoproteins act remain unknown. Recently, an oncogene, v- jun , was found to share homology with the DNA binding domain of a yeast transcription factor,
D, Bohmann, T J, Bos, A, Admon, T, Nishimura, P K, Vogt, R, Tjian   +5 more
openaire   +3 more sources