Results 141 to 150 of about 20,673,795 (179)

Copy Number Amplification and c-Myc Transcriptional Activation-Mediated RNA-Binding Protein MEX3A Promotes EGFR-TKI Resistance in Non-Small-Cell Lung Cancer. [PDF]

Thorac Cancer
Xiling S, Lin D, Jiali D, Chen Z, Ruohan H, Chang Z, Renhua G, Jun L.   +7 more
europepmc   +1 more source

The Small Molecule Compound Eupalinolide B Ameliorates Depressive Behaviors and Neuropathic Pain in Mice With Spared Nerve Injury: Integrating Network Pharmacology, Molecular Docking, Bioinformatics, Molecular Dynamics Simulation and Experimental Verification. [PDF]

CNS Neurosci Ther
Yang X, Jiang F, Wu Y, Chen K, Xiang H.
europepmc   +1 more source

Exploring the mechanism of the Lianshi Jianpi formula in treating impaired glucose tolerance: a network pharmacology, molecular docking, and experimental validation study. [PDF]

J Tradit Chin Med
Mingqian J, Tong W, Bowei H, Chen Q, Yanbin L, Binhua YE.   +5 more
europepmc   +1 more source

Integrated Metabolomics, Network Pharmacology, and Molecular Dynamics Simulations Reveal the Potential Anti-Melanoma Mechanisms of <i>Inonotus hispidus</i>. [PDF]

Curr Issues Mol Biol
Liu H, Liu J, Ma Z, Li H, Liu X, Zhu D.
europepmc   +1 more source

SF1 regulates the transcription of FDX1 to promote cuproptosis in pediatric sepsis-related acute lung injury by interacting with cJUN. [PDF]

Biol Direct
Wang Y, Sun J, Zhang L, Zhou S, Zhao F.
europepmc   +1 more source

Elucidating the beneficial effects of gut microbiota-derived metabolites in treating hepatocellular carcinoma: an integrated network pharmacology, molecular docking, and single-cell sequencing analysis. [PDF]

Bioresour Bioprocess
Huo J, Song W, Sun Y, Lu J, Wang M.
europepmc   +1 more source

Comprehensive transcriptomic characterization of two melanoma cell lines with acquired dual resistance to BRAF and MEK inhibitors. [PDF]

Sci Rep
Kujawa T, Simiczyjew A, Kot M, Gambin T, Nowak D, Kobiela T.   +5 more
europepmc   +1 more source

Angiotensin-II-induced expression of proto-oncogene (c-fos,jun-B and c-jun) mRNA in bovine adrenocortical fasciculata cells (BAC) is mediated by AT-1 receptors [PDF]

FEBS Letters, 1992
We have shown previously that angiotensin-II (A-II) controls proto-oncogene (c-fos, jun-B and c-jun) mRNA accumulation in bovine adrenal fasciculata cells (BAC).
J M Sáez
exaly   +2 more sources

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Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation.

Alcohol and alcoholism (Oxford, Oxfordshire), 1994
Hepatic fibrosis is an important morphological feature of alcohol-induced liver injury. We previously reported that acetaldehyde stimulates collagen I and fibronectin gene transcription in rat fat-storing cell (FSC) culture. We here evaluated whether acetaldehyde increases Col I and FN gene transcription through the induction of c-fos and c-jun proto ...
CASINI, ALESSANDRO, GALLI, GIANNA, R. SALZANO, CENI, ELISABETTA, F. FRANCESCHELLI, ROTELLA, CARLO MARIA, SURRENTI, CALOGERO   +6 more
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Induction of the c-jun proto-oncogene by a protein kinase c-dependent mechanism during exposure of human epidermal keratinocytes to ethanol

Biochemical Pharmacology, 1993
The present work demonstrates that ethanol induces expression of the c-jun proto-oncogene in human keratinocytes. Increased c-jun mRNA levels were detectable at 1 hr of exposure to 1% ethanol and at 24 hr remained above that in control keratinocytes. An increase in c-jun expression was also detectable at ethanol concentrations of 0.1 and 0.5%.
S, Kharbanda, T, Nakamura, D, Kufe
openaire   +2 more sources