Results 141 to 150 of about 75,334 (151)

Correlation between lack of bone Gla protein mRNA expression in rat transplantable osteosarcomas and expression of both c‐fos and c‐jun proto‐oncogenes

open access: closedMolecular Carcinogenesis, 1993
AbstractAlkaline phosphatase (AP) activity and expression of bone Gla protein (BGP), c‐fos, and c‐jun were compared in two transplantable osteosarcomas with high potentials for metastasis to the lung. The original spontaneous osteosarcoma (SOS) gradually became histologically undifferentiated, losing its osteogenic activity during serial transfer ...
Kanya Honoki   +11 more
openaire   +3 more sources

Localization of C-FOS and C-JUN proto-oncogene proteins in rat pleural mesothelial cells by immunofluorescence and confocal scanning laser microscopy

open access: closedProceedings, annual meeting, Electron Microscopy Society of America, 1995
The proto-oncogenes c-fos and c-jun are members of a multigene family known as immediate early genes (IEG) that are transiently expressed in response to a wide variety of environmental stimuli. Homodimeric complexes of jun gene-family products and heterodimeric complexes of the jun and fos gene-family products form the transcription factor AP-1, which ...
K.A. BéruBé   +3 more
openaire   +2 more sources

Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells.

open access: closedCancer research, 1997
Asbestos and the phorbol ester tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), increase c-fos and c-jun mRNA levels and AP-1 DNA binding activity in rat pleural mesothelial (RPM) cells, a target cell of asbestos-induced mesotheliomas (N. H. Heintz et al., Proc. Natl. Acad. Sci. USA, 90: 3299-3303, 1993).
H, Fung   +9 more
openaire   +2 more sources

Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel.

open access: closedOncogene, 1996
The transcription factor v-Rel is a transforming protein of the reticuloendotheliosis virus. We found that v-Rel activates the promoter of the proto-oncogene c-jun. Two elements in the c-jun promoter were required for the activation by v-Rel. One was a kB-site (v-Rel binding site), and the other was a c-jun promoter region between -52 and +148 (c-jun ...
M, Fujii   +5 more
openaire   +2 more sources

Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress.

open access: closedCancer research, 2001
Crystalline silica has been classified as a group 1 human carcinogen in the lung. However, its mechanisms of action on pulmonary epithelial cells which give rise to lung cancers are unclear. Using a nontransformed alveolar type II epithelial cell line (C10), we show that alpha-quartz silica causes persistent dose-related increases in phosphorylation of
A, Shukla   +4 more
openaire   +2 more sources
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[Effects of acrylamide on the protein expressions of c-fos and c-jun proto-oncogenes in cell L-02].

Wei sheng yan jiu = Journal of hygiene research, 2012
To investigate the cell apoptosis and expressions of c-fos and c-jun proteins induced by acrylamide (AA) in L-02 human liver embryo cell.The cell survival rate, cell apoptosis and protein expressions of c-fos and c-jun were measured respectively after L-02 cell were exposed to different final concentration of AA (low: 0.01, 0.1 mmol/l; middle: 0.1, 0.5,
Rui, Wang   +5 more
openaire   +1 more source

[Rules of protein expression of proto-oncogene (c-Fos/c-Jun) in different brain areas and nucleus of psychological stressed mice and the regulatory effect of modified Xiaoyao Pill].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2008
To study the rules of protein expression of proto-oncogene (c-Fos/c-Jun) in different brain areas and nucleus of psychological stressed mice and the regulatory effect of modified Xiaoyao Pill (SXP).The mouse psychological stress model was established by electrical stimulation; SXP was administrated at the dose of 2 mg/g; the protein expression of c-Fos
Zhen-yu, Wu, Yun, Zhang, Jian, Xiao
openaire   +1 more source

[Effects of acrylamide on the protein expressions of c-fos and c-jun proto-oncogenes in cell L-02].

open access: closed, 2010
Rui Wang   +5 more
openalex  

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