Background The second most common cancer in the world is breast cancer. Chemotherapy is used to treat breast cancer, but instances of multidrug resistance, targets that are not selective, and physicochemical issues raise doubts about its efficacy.
Aida I. El makawy+7 more
doaj +1 more source
Biologia molecular do câncer cervical Molecular biology of cervical cancer
A carcinogênese é um processo de múltiplas etapas. Alterações no equilíbrio citogenético ocorrem na transformação do epitélio normal a câncer cervical. Numerosos estudos apoiam a hipótese de que a infecção por HPV está associada com o desenvolvimento de ...
Waldemar Augusto Rivoire+3 more
doaj +1 more source
Pediatric Cancers: Development and Treatment Methods
Pediatric cancers are cancers that develop in kids and adolescents ages 0-19. Pediatric cancers usually develop in three ways: through inherited gene mutations, parental exposure to toxins, and acquired gene mutations.
Walker, MaKayla M.
core
Retroviral insertions in Evi12, a novel common virus integration site upstream of Tra1/Grp94, frequently coincide with insertions in the gene encoding the peripheral cannabinoid receptor Cnr2 [PDF]
The common virus integration site (VIS) Evi11 was recently identified within the gene encoding the hematopoietic G-protein-coupled peripheral cannabinoid receptor Cnr2 (also ...
Copeland, N.G.+6 more
core
Polyploidy and Myc Proto-Oncogenes Promote Stress Adaptation via Epigenetic Plasticity and Gene Regulatory Network Rewiring. [PDF]
Anatskaya OV, Vinogradov AE.
europepmc +1 more source
Diagnostic Biomarkers Related to Cancer Detection and Treatment: A Review Article
Cancer is a serious problem affecting the health of all human societies. Thus the challenge is how the diagnosis and then who find effective treatment. Proto-oncogenes under abnormal condition turn out to be oncogenes throughout genetic mutation, which ...
.Suhad Faisal Hatem Al-Mugdadi
doaj
MOLECULAR-GENETIC «PORTRAIT» OF BREAST CANCER
Understanding genetic mechanisms and detection of biological markers of tumor growth forms an individual molecular phenotype oftransformed cells that characterizes stage of tumor, the ability to metastasize, hormonal sensitivity ...
S. A. Laptiev+2 more
doaj +1 more source
Mutations of ras genes in human tumours (Review) [PDF]
Journal URL: http://www.spandidos-publications.com/ijo/Ras family genes (H-, K- and N-ras) are implicated in a wide range of human tumours. Mutations are a major activating mechanism for the ras family genes, mainly in codons 12, 13 and 61, resulting in ...
Kiaris, H., Spandidos, D. A.
core
The RET Proto-Oncogene in Sporadic Pheochromocytomas.
In order to evaluate the role of RET proto-oncogene in the development and growth of pheochromocytomas, we examined mutations in RET and expression of RET in 7 cases of sporadic pheochromocytomas. Tumors were screened for mutations in exons 10 and 11 and codon 918 which are identified in multiple endocrine neoplasia types 2A and 2B.
Yoshihiro Miyamoto+6 more
openaire +4 more sources
Multiomics Study of a Novel Naturally Derived Small Molecule, NSC772864, as a Potential Inhibitor of Proto-Oncogenes Regulating Cell Cycle Progression in Colorectal Cancer. [PDF]
Mokgautsi N+5 more
europepmc +1 more source