Polyploidy and Myc Proto-Oncogenes Promote Stress Adaptation via Epigenetic Plasticity and Gene Regulatory Network Rewiring. [PDF]
Int J Mol Sci, 2022 Anatskaya OV, Vinogradov AE.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
MOLECULAR-GENETIC «PORTRAIT» OF BREAST CANCER
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017 Understanding genetic mechanisms and detection of biological markers of tumor growth forms an individual molecular phenotype oftransformed cells that characterizes stage of tumor, the ability to metastasize, hormonal sensitivity ...
S. A. Laptiev +2 more
doaj +1 more source
Multiomics Study of a Novel Naturally Derived Small Molecule, NSC772864, as a Potential Inhibitor of Proto-Oncogenes Regulating Cell Cycle Progression in Colorectal Cancer. [PDF]
Cells, 2023 Mokgautsi N +5 more
europepmc +1 more source
Investigation of the structural and functional relationships of oneogene proteins [PDF]
, 2002 Proteins are the biomolecular workhorses driving the most biological processes in any living organism. These processes are based on selective interactions between particular proteins.
Akay, M, Cosic, I, Fang, J, Pirogova, E
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Biologia molecular do câncer cervical Molecular biology of cervical cancer
Revista Brasileira de Saúde Materno Infantil, 2006 A carcinogênese é um processo de múltiplas etapas. Alterações no equilíbrio citogenético ocorrem na transformação do epitélio normal a câncer cervical. Numerosos estudos apoiam a hipótese de que a infecção por HPV está associada com o desenvolvimento de ...
Waldemar Augusto Rivoire +3 more
doaj +1 more source
Post-prostatic-massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate-cancer-typical microRNAs and activate proto-oncogenes. [PDF]
Mol Oncol, 2023 Schneider L +7 more
europepmc +1 more source
Investigation of c-Myc gene amplification in breast cancer patients and its correlation with other prognostic factors [PDF]
, 2018 Background: Breast cancer is the most common cancer in woman. The frequency of amplification of some proto-oncogenes like c-Myc gene may be various in different populations.
Akbari, Mohammad Esmaeel +2 more
core
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source