Results 91 to 100 of about 325,026 (325)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Biologia molecular do câncer cervical Molecular biology of cervical cancer

open access: yesRevista Brasileira de Saúde Materno Infantil, 2006
A carcinogênese é um processo de múltiplas etapas. Alterações no equilíbrio citogenético ocorrem na transformação do epitélio normal a câncer cervical. Numerosos estudos apoiam a hipótese de que a infecção por HPV está associada com o desenvolvimento de ...
Waldemar Augusto Rivoire   +3 more
doaj   +1 more source

Variable finals in proto-Sino-Tibetan

open access: yes, 2010
This paper concentrates on variable finals, and argues that just as we find a certain amount of both rule-governed and non-rule governed variation in modern languages, in reconstructing Proto-Sino-Tibetan we should recognize the possibility of these ...
LaPolla, Randy J.
core  

Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease.

open access: yes, 1987
DNAs from fifty-three primary breast cancers were hybridized with 16 different proto-oncogene or oncogene probes. Abnormalities of one or more of five proto-oncogenes were found in fifty-eight percent of tumors at the time of mastectomy.
J Yokota, M J Cline, H Battifora
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

MOLECULAR-GENETIC «PORTRAIT» OF BREAST CANCER

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Understanding genetic mechanisms and detection of biological markers of tumor growth forms an individual molecular phenotype oftransformed cells that characterizes stage of tumor, the ability to metastasize, hormonal sensitivity ...
S. A. Laptiev   +2 more
doaj   +1 more source

The effects of ectopic expression of TAL1 and LMO1 on lipoprotein lipase in NIH 3T3 cells

open access: yes, 2003
Childhood acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Several proto-oncogenes that encode nuclear proteins are activated by various chromosomal translocations in ALL including TALI, TAL2, and LMO1 and LMO2.
Haeri, Hosseini S. Mohammad.
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

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