Results 11 to 20 of about 2,480 (202)
Selection for Replicases in Protocells [PDF]
PLoS Computational Biology, 2013 We consider a world of nucleotide sequences and protocells. The sequences have the property of spontaneous self-replication. Some sequences - so-called replicases - have enzymatic activity in the sense of enhancing the replication rate of all (or almost all) sequences.
Bianconi, Ginestra +4 more
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SYNCHRONIZATION PHENOMENA IN PROTOCELL MODELS [PDF]
BIOMAT 2007, 2008 This work aims to consider simplified models of protocells in order to describe their general behaviors. The advantage of the modelling approach is that the early protocells of life-forms on Earth are not reproduced in the present time. However, the problem is considered as a right track to understand the origin of life as well as to work with more ...
FILISETTI, alessandro +4 more
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Colony-like Protocell Superstructures [PDF]
Biophysical Journal, 2021 Abstract We report the formation, growth, and dynamics of model protocell superstructures on solid surfaces, resembling single cell colonies. These structures, consisting of several layers of lipidic compartments enveloped in a dome-shaped outer lipid bilayer, emerged as a result of spontaneous shape transformation of lipid agglomerates
Katke, Chinmay +5 more
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On Protocell "Computation" [PDF]
, 2006 The EU FP6 Integrated Project PACE ('Programmable Artificial Cell Evolution') is investigating the creation, de novo, of chemical 'protocells'. These will be minimal 'wetware' chemical systems integrating molecular information carriers, primitive energy ...
Kelly, Ciarán +2 more
core +4 more sources
Spatially Encoded Protocell Network for Non-Cascaded Parallel Biocomputation. [PDF]
Adv Sci (Weinh)A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Wu S, Tian L.
europepmc +2 more sources
, 2010 A protocell is defined as the earliest form of chemical system that can replicate itself. Although cells inevitably contain some form of metabolism to achieve this goal, the cell was originally thought of and thus named by its enclosing structure. We now know that the structure is built by a cellular metabolism which is regulated and produced by an ...
Maurer, Sarah
core +3 more sources
Photoactivated Signaling Networks using DNA-Based Synthetic Organelles as Biomimetic Protocells. [PDF]
Angew Chem Int Ed EnglLight‐triggered intercommunication between two types of organelle‐loaded liposomes lead to DNAzyme‐mediated on transcription‐guided structural reconfiguration of the organelles. ABSTRACT Membraneless organelles formed by phase‐separated nucleic acid or protein condensates play vital roles in regulating cellular functions.
Xue H +6 more
europepmc +3 more sources
Current Biology, 2020 Lai and Chen introduce the role of compartmentalization in the evolution of life.
Yei-Chen, Lai, Irene A, Chen
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Non-interfacial self-assembly of synthetic protocells
Biomaterials Research, 2023 Background Protocell refers to the basic unit of life and synthetic molecular assembly with cell structure and function. The protocells have great applications in the field of biomedical technology.
Xiaolin Xu +4 more
doaj +1 more source
Evolution of Proliferative Model Protocells Highly Responsive to the Environment
Life, 2022 In this review, we discuss various methods of reproducing life dynamics using a constructive approach. An increase in the structural complexity of a model protocell is accompanied by an increase in the stage of reproduction of a compartment (giant ...
Muneyuki Matsuo +3 more
doaj +1 more source