Results 31 to 40 of about 3,765 (199)
The limits of metabolic heredity in protocells [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2022 The universal core of metabolism could have emerged from thermodynamically favoured prebiotic pathways at the origin of life. Starting with H 2 and CO 2 , the synthesis of amino acids and mixed fatty acids, which self-assemble into protocells, is ...
Raquel Nunes Palmeira +4 more
openaire +3 more sources
Designing with Protocells: Applications of a Novel Technical Platform
Life, 2014 The paper offers a design perspective on protocell applications and presents original research that characterizes the life-like qualities of the Bütschli dynamic droplet system, as a particular “species” of protocell.
Rachel Armstrong
doaj +1 more source
Electrostatically gated membrane permeability in inorganic protocells [PDF]
, 2013 Although several strategies are now available to produce functional microcompartments analogous to primitive cell-like structures, little progress has been made in generating protocell constructs with self-controlled membrane permeability.
A Boker +30 more
core +4 more sources
Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow
Life, 2014 Over the past few decades, several protocell models have been developed that mimic certain essential characteristics of living cells. These protocells tend to be highly reductionist simplifications of living cells with prominent bilayer membrane ...
Martin M Hanczyc
doaj +1 more source
Natural selection. III. Selection versus transmission and the levels of selection [PDF]
, 2011 George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission.
Frank, Steven A.
core +2 more sources
Life, 2022 Although numerous reports using methods such as molecular dynamics, cellular automata, and artificial chemistry have clarified the process connecting non-life and life on protocell simulations, none of the models could simultaneously explain the ...
Takeshi Ishida
doaj +1 more source
Photoactivated Signaling Networks using DNA‐Based Synthetic Organelles as Biomimetic Protocells
Angewandte Chemie, EarlyView.Light‐triggered intercommunication between two types of organelle‐loaded liposomes lead to DNAzyme‐mediated on transcription‐guided structural reconfiguration of the organelles. ABSTRACT Membraneless organelles formed by phase‐separated nucleic acid or protein condensates play vital roles in regulating cellular functions.
Huiying Xue +6 more
wiley +2 more sources
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]
, 2011 Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E +20 more
core +2 more sources
Evolution of oil droplets in a chemorobotic platform [PDF]
, 2014 Evolution, once the preserve of biology, has been widely emulated in software, while physically embodied systems that can evolve have been limited to electronic and robotic devices and have never been artificially implemented in populations of physically
Cronin, Leroy +4 more
core +2 more sources
Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems
Life, 2019 In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the
Vismay Shah +4 more
doaj +1 more source