Results 31 to 40 of about 2,480 (202)

Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays [PDF]

open access: yes, 2019
Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to ...
Tian, Liangfei   +7 more
core   +1 more source

Triggerable Protocell Capture in Nanoparticle-Caged Coacervate Microdroplets [PDF]

open access: yes, 2022
Controlling the dynamics of mixed communities of cell-like entities (protocells) provides a step toward the development of higher-order cytomimetic behaviors in artificial cell consortia.
Gao, Ning   +9 more
core   +3 more sources

Designing with Protocells: Applications of a Novel Technical Platform

open access: yesLife, 2014
The paper offers a design perspective on protocell applications and presents original research that characterizes the life-like qualities of the Bütschli dynamic droplet system, as a particular “species” of protocell.
Rachel Armstrong
doaj   +1 more source

Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow

open access: yesLife, 2014
Over the past few decades, several protocell models have been developed that mimic certain essential characteristics of living cells. These protocells tend to be highly reductionist simplifications of living cells with prominent bilayer membrane ...
Martin M Hanczyc
doaj   +1 more source

Engineering coacervate droplets towards the building of multiplex biomimetic protocells

open access: yesSupramolecular Materials, 2022
The origin of life on Earth remains one of the biggest open questions in science. Despite recent advances in molecular mechanism of cell biology, a large blind spot still exists between non-living matter and the emergence of life which cannot be filled ...
Hua Wu, Yan Qiao
doaj   +1 more source

The limits of metabolic heredity in protocells [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2022
The universal core of metabolism could have emerged from thermodynamically favoured prebiotic pathways at the origin of life. Starting with H 2 and CO 2 , the synthesis of amino acids and mixed fatty acids, which self-assemble into protocells, is ...
Raquel Nunes Palmeira   +4 more
openaire   +3 more sources

Fatty Acid Vesicles as Hard UV-C Shields for Early Life

open access: yesFoundations, 2023
Theories on life’s origin generally acknowledge the advantage of a semi-permeable vesicle (protocell) for enhancing the chemical reaction–diffusion processes involved in abiogenesis.
Iván Lechuga, Karo Michaelian
doaj   +1 more source

Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems

open access: yesLife, 2019
In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the
Vismay Shah   +4 more
doaj   +1 more source

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

open access: yesBeilstein Journal of Organic Chemistry, 2017
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss   +2 more
doaj   +1 more source

Toward Spatially Regulated Division of Protocells: Insights into the E. coli Min System from in Vitro Studies

open access: yesLife, 2014
For reconstruction of controlled cell division in a minimal cell model, or protocell, a positioning mechanism that spatially regulates division is indispensable.
Simon Kretschmer, Petra Schwille
doaj   +1 more source

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