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Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
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Progress in synthesizing protocells [PDF]
Experimental Biology and Medicine, 2018 The traditional route to investigating biology by perturbing living systems or by individually purifying and characterizing component parts is giving way to more complex endeavors where chemists and physicists attempt to build cells from scratch. Parallel efforts are underway that either exploits extant biological parts or prebiotically plausible ...
Toparlak, Omer Duhan, Mansy, Sheref S.
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Introduction. Artificial protocells [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2007 What makes a cell? How are cells able to replicate themselves in a stable manner? How did cellular life emerge on our planet? The answer to these fundamental questions lies at the base of biology.
Solé, Richard V. +2 more
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Engineering coacervate droplets towards the building of multiplex biomimetic protocells
Supramolecular Materials, 2022 The origin of life on Earth remains one of the biggest open questions in science. Despite recent advances in molecular mechanism of cell biology, a large blind spot still exists between non-living matter and the emergence of life which cannot be filled ...
Hua Wu, Yan Qiao
doaj +1 more source
Effect of migration in a diffusion model for template coexistence in protocells [PDF]
, 2014 The compartmentalization of distinct templates in protocells and the exchange of templates between them (migration) are key elements of a modern scenario for prebiotic evolution.
Fontanari, Jose F., Serva, Maurizio
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A stochastic model of catalytic reaction networks in protocells [PDF]
, 2014 Protocells are supposed to have played a key role in the self-organizing processes leading to the emergence of life. Existing models either (i) describe protocell architecture and dynamics, given the existence of sets of collectively self-replicating ...
Damiani, Chiara +5 more
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Fatty Acid Vesicles as Hard UV-C Shields for Early Life
Foundations, 2023 Theories on life’s origin generally acknowledge the advantage of a semi-permeable vesicle (protocell) for enhancing the chemical reaction–diffusion processes involved in abiogenesis.
Iván Lechuga, Karo Michaelian
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Accounts of Chemical Research, 2012 Prebiotic soup experiments have shown that the molecular building blocks of life can be built under prebiotically plausible conditions. From this starting point, researchers have launched continued studies of polymerization and explorations of the breadth of RNA function.
Del Bianco, Cristina +1 more
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The origin of heredity in protocells [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Here we develop a computational model that examines one of the first major biological innovations—the origin of heredity in simple protocells. The model assumes that the earliest protocells were autotrophic, producing organic matter from CO 2 and H 2 .
West, T +3 more
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Selfishness versus functional cooperation in a stochastic protocell model [PDF]
, 2010 How to design an "evolvable" artificial system capable to increase in complexity? Although Darwin's theory of evolution by natural selection obviously offers a firm foundation, little hope of success seems to be expected from the explanatory adequacy of ...
Agresti +56 more
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