Results 41 to 50 of about 2,480 (202)
The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume [PDF]
, 2011 We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the ...
Carletti, Timoteo; id_orcid +5 more
core +1 more source
Spontaneous Membranization in a Silk‐Based Coacervate Protocell Model
, 2022 A dynamic alginate/silk coacervate-based protocell model capable of reversible reconfigurations between semipermeable coacervate vesicles and membrane-less coacervate droplets is described.
Stephen Mann +10 more
core +1 more source
Chemical-mediated translocation in protocell-based micro-actuators [PDF]
, 2021 Artificial cell-like communities participate in diverse modes of chemical interaction but exhibit minimal interfacing with their local environment. Here we develop an interactive micro-system based on the immobilization of a population of enzyme-active ...
Gao, Ning +11 more
core +1 more source
On the Growth Rate of Non-Enzymatic Molecular Replicators
Entropy, 2011 It is well known that non-enzymatic template directed molecular replicators X + nO -> 2X exhibit parabolic growth d[X]/dt -> k[X]1/2. Here, we analyze the dependence of the effective replication rate constant k on hybridization energies ...
Harold Fellermann, Steen Rasmussen
doaj +1 more source
Life, 2017 One of the key steps in the origins of life was the formation of a membrane to separate protocells from their environment. These membranes are proposed to have been formed out of single chain amphiphiles, which are less stable than the dialkyl lipids ...
Sarah Maurer
doaj +1 more source
Protocells: Milestones and Recent Advances
Small, 2022 AbstractThe origin of life is still one of humankind's great mysteries. At the transition between nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain the structure and functions necessary to fulfill the criteria of life.
Gözen, Irep +8 more
openaire +5 more sources
The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity
Life, 2022 The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
doaj +1 more source
Nanoporous Silica-Based Protocells at Multiple Scales for Designs of Life and Nanomedicine
Life, 2015 Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Jie Sun +3 more
doaj +1 more source
Life, 2021 Metal ions strongly affect the self-assembly and stability of membranes composed of prebiotically relevant amphiphiles (protoamphiphiles). Therefore, evaluating the behavior of such amphiphiles in the presence of ions is a crucial step towards assessing ...
Manesh Prakash Joshi +3 more
doaj +1 more source
SURFACE-REACTION MODELS OF PROTOCELLS
BIOMAT 2006, 2007 We present a class of models aiming to describe generic protocells hypotheses, improving a model introduced elsewhere[13]. These models, inspired by the 'Los Alamos bug' hypothesis, are composed by two coupled subsystems: a self-replicating molecule-SRM- and a lipid container.
SERRA, Roberto, T. CARLETTI, I. POLI
openaire +5 more sources