Results 41 to 50 of about 3,765 (199)

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

open access: yesBeilstein Journal of Organic Chemistry, 2017
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss   +2 more
doaj   +1 more source

Toward Spatially Regulated Division of Protocells: Insights into the E. coli Min System from in Vitro Studies

open access: yesLife, 2014
For reconstruction of controlled cell division in a minimal cell model, or protocell, a positioning mechanism that spatially regulates division is indispensable.
Simon Kretschmer, Petra Schwille
doaj   +1 more source

Autonomous model protocell division driven by molecular replication [PDF]

open access: yes, 2017
The coupling of compartmentalisation with molecular replication is thought to be crucial for the emergence of the first evolvable chemical systems. Minimal artificial replicators have been designed based on molecular recognition, inspired by the template
Cronin, L.   +4 more
core   +1 more source

On the Growth Rate of Non-Enzymatic Molecular Replicators

open access: yesEntropy, 2011
It is well known that non-enzymatic template directed molecular replicators X + nO -> 2X exhibit parabolic growth d[X]/dt -> k[X]1/2. Here, we analyze the dependence of the effective replication rate constant k on hybridization energies ...
Harold Fellermann, Steen Rasmussen
doaj   +1 more source

The Impact of Salts on Single Chain Amphiphile Membranes and Implications for the Location of the Origin of Life

open access: yesLife, 2017
One of the key steps in the origins of life was the formation of a membrane to separate protocells from their environment. These membranes are proposed to have been formed out of single chain amphiphiles, which are less stable than the dialkyl lipids ...
Sarah Maurer
doaj   +1 more source

The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity

open access: yesLife, 2022
The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
doaj   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

open access: yesAngewandte Chemie, Volume 138, Issue 17, 20 April 2026.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe   +5 more
wiley   +2 more sources

Influence of Metal Ions on Model Protoamphiphilic Vesicular Systems: Insights from Laboratory and Analogue Studies

open access: yesLife, 2021
Metal ions strongly affect the self-assembly and stability of membranes composed of prebiotically relevant amphiphiles (protoamphiphiles). Therefore, evaluating the behavior of such amphiphiles in the presence of ions is a crucial step towards assessing ...
Manesh Prakash Joshi   +3 more
doaj   +1 more source

Origin of Species before Origin of Life: The Role of Speciation in Chemical Evolution

open access: yesLife, 2021
Speciation, an evolutionary process by which new species form, is ultimately responsible for the incredible biodiversity that we observe on Earth every day.
Tony Z. Jia   +2 more
doaj   +1 more source

SURFACE-REACTION MODELS OF PROTOCELLS

open access: yesBIOMAT 2006, 2007
We present a class of models aiming to describe generic protocells hypotheses, improving a model introduced elsewhere[13]. These models, inspired by the 'Los Alamos bug' hypothesis, are composed by two coupled subsystems: a self-replicating molecule-SRM- and a lipid container.
SERRA, Roberto, T. CARLETTI, I. POLI
openaire   +5 more sources

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