Results 61 to 70 of about 3,765 (199)
Protocells: Milestones and Recent Advances
Small, 2022 AbstractThe origin of life is still one of humankind's great mysteries. At the transition between nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain the structure and functions necessary to fulfill the criteria of life.
Gözen, Irep +8 more
openaire +5 more sources
Small, EarlyView.Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han +6 more
wiley +1 more source
Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis
Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han +7 more
wiley +2 more sources
Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.In this work, the synthesis and characterization of novel π‐extended phenazine diimides is reported. The derivatives undergo differential reduction to a dihydrophenazine or Meisenheimer form depending on the reaction conditions employed. The outcome of this work highlights the paramount importance of structural design in determining the nature of the ...
Francesco Rigodanza +7 more
wiley +1 more source
Small Science, Volume 6, Issue 5, May 2026.Amine‐functionalized block copolymer nanoparticles were synthesized via RAFT‐PISA with rigorous quantification of interfacial amine accessibility. The surface‐reactive amines served as modular handles for postassembly conjugation with fluorescent dyes and thermoresponsive polymers, conferring optical trackability and stimuli‐responsive behaviors ...
Aharon Steffè +6 more
wiley +1 more source
What Does “the RNA World” Mean to “the Origin of Life”?
Life, 2017 Corresponding to life’s two distinct aspects: Darwinian evolution and self-sustainment, the origin of life should also split into two issues: the origin of Darwinian evolution and the arising of self-sustainment. Because the “self-sustainment” we concern
Wentao Ma
doaj +1 more source
On the Terminology of Lipid Nanoparticles, Liposomes, and Vesicles
ChemSystemsChem, Volume 8, Issue 3, May 2026.The terms “liposome,” “vesicle,” and “lipid nanoparticle” (LNP) should be defined clearly to avoid conceptual and practical errors. Structures and distinctions are introduced here for nonspecialists. Overly broad use of “LNP” to refer to any nanosized, lipid‐based assemblage is discouraged.
Irene A. Chen
wiley +1 more source
Preliminary steps toward artificial protocell computation [PDF]
, 2007 Protocells are hypothesised as a transitional phase in the origin of life, prior to the evolution of fully functional prokaryotic cells. The work reported here is being done in the context of the PACE project, which is investigating the fabrication of ...
Decraene, James +4 more
core +1 more source
RNA catalysis in model protocell vesicles. [PDF]
, 2005 We are engaged in a long-term effort to synthesize chemical systems capable of Darwinian evolution, based on the encapsulation of self-replicating nucleic acids in self-replicating membrane vesicles.
Chen, Irene A +2 more
core +2 more sources
Coevolution of compositional protocells and their environment [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2007 The coevolution of environment and living organisms is well known in nature. Here, it is suggested that similar processes can take place before the onset of life, where protocellular entities, rather than full-fledged living systems, coevolve along with their surroundings.
Barak, Shenhav, Aia, Oz, Doron, Lancet
openaire +2 more sources