Results 61 to 70 of about 2,480 (202)
Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration
Biotechnology and Bioengineering, EarlyView.ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi +2 more
wiley +1 more source
Growth and Division in a Dynamic Protocell Model
Life, 2014 In this paper a new model of growing and dividing protocells is described, whose main features are (i) a lipid container that grows according to the composition of the molecular milieu (ii) a set of “genetic memory molecules” (GMMs) that undergo ...
Marco Villani +5 more
doaj +1 more source
Bioinspired Networks of Communicating Synthetic Protocells
Frontiers in Molecular Biosciences, 2021 The bottom-up synthesis of cell-like entities or protocells from inanimate molecules and materials is one of the grand challenges of our time. In the past decade, researchers in the emerging field of bottom-up synthetic biology have developed different ...
Patrick J. Grimes +4 more
doaj +1 more source
Negative Chemotaxis of Urease‐Functionalized Polymeric Microcapsules
Small, EarlyView.Urease‐functionalized PLGA microcapsules exhibit negative chemotaxis in urea gradients, migrating from high to low substrate concentrations. Increasing gradients enhance chemotaxis until a plateau, while increasing average substrate concentration in a fixed gradient reverses chemotactic behavior.
Amanda Hopkins +2 more
wiley +1 more source
Protocells and RNA Self-Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The general notion of an "RNA world" is that, in the early development of life on the Earth, genetic continuity was assured by the replication of RNA, and RNA molecules were the chief agents of catalytic function. Assuming that all of the components of RNA were available in some prebiotic locale, these components could have assembled into activated ...
Gerald F. Joyce, Jack W. Szostak
openaire +2 more sources
Life, 2019 Protocells are supramolecular systems commonly used for numerous applications, such as the formation of self-evolvable systems, in systems chemistry and synthetic biology.
Augustin Lopez, Michele Fiore
doaj +1 more source
Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes
Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis +1 more
wiley +1 more source
A Hypothesis for Protocell Division on the Early Earth
, 2019 I hypothesize that the division of the first protocell might have occurred before genetic polymers were synthesized and redistributed. In the light of recent findings, it is conceivable that the first division event of a primitive protocell might have ...
Gözen, Irep,, G\uf6zen, Irep
core +1 more source
Small Science, Volume 6, Issue 11, November 2026.The rational design of novel glycolipid‐based self‐coacervates by tuning attractive (pi–pi and H‐bonding) and repulsive (electrostatic) interactions is reported. The low‐molecular‐weight glycolipid‐based MWGSD‐A4 coacervates can encapsulate dyes, drugs, proteins, and pathogenic viruses.
Nikesh Dewangan +8 more
wiley +1 more source
Chemical systems, chemical contiguity and the emergence of life
Beilstein Journal of Organic Chemistry, 2017 Charting the emergence of living cells from inanimate matter remains an intensely challenging scientific problem. The complexity of the biochemical machinery of cells with its exquisite intricacies hints at cells being the product of a long evolutionary ...
Terrence P. Kee, Pierre-Alain Monnard
doaj +1 more source