Results 71 to 80 of about 2,480 (202)
Theoretical perspective on synthetic man‐made life: Learning from the origin of life
Quantitative Biology, 2023 Creating a man‐made life in the laboratory is one of life science’s most intriguing yet challenging problems. Advances in synthetic biology and related theories, particularly those related to the origin of life, have laid the groundwork for further ...
Lu Peng +11 more
doaj +1 more source
Toward Ideal Proximity‐Driven Reactions in Chemical Biology
ChemBioChem, Volume 27, Issue 19, 14 October 2026.Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Dominik Schauenburg
wiley +1 more source
From Vesicles to Protocells: The Roles of Amphiphilic Molecules
Life, 2015 It is very challenging to construct protocells from molecular assemblies. An important step in this challenge is the achievement of vesicle dynamics that are relevant to cellular functions, such as membrane trafficking and self-reproduction, using ...
Yuka Sakuma, Masayuki Imai
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Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.ATP itself is able to undergo liquid–liquid phase separation in the presence of the macromolecular crowding agent PEG and physiological ATP concentrations are sufficient for phase separation in the presence of mM Mg2+ and crowders, mimicking intracellular conditions.
Robert Dec +2 more
wiley +1 more source
Predatory behaviour in synthetic protocell communities [PDF]
, 2017 Recent progress in the chemical construction of colloidal objects comprising integrated biomimetic functions is paving the way towards rudimentary forms of artificial cell-like entities (protocells). Although several new types of protocells are currently
Stephen Mann +7 more
core +1 more source
Programming Multidomain Peptides With Molecular Frustration Into Biomolecular Condensates
Small, Volume 22, Issue 51, 11 September 2026.De novo designed multidomain peptides (MDPs) were used to explore how molecular ordering influences peptide phase behavior. MDPs containing partially folded β‐sheets were found to form biomolecular condensates. This work introduces a new design principle for condensate formation and expand the design space beyond conventional intrinsically disordered ...
Debdatta Das +12 more
wiley +1 more source
Mode Switching and Collective Behavior in Chemical Oil Droplets
Entropy, 2011 We have characterized several dynamic aspects of a simple chemical system capable of self-movement: An oil droplet in water system. We focused on spontaneous mode switching and collective behavior of droplets as emergent properties of the system ...
Takashi Ikegami +2 more
doaj +1 more source
Design of Fuel‐Dependent, Complex‐Coacervate‐Based Synthetic Cells
Chemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.Fuel‐dependent synthetic cells form and persist only in the presence of chemical fuel, decaying under starvation. We establish design rules for hexapeptide‐based coacervates, showing that tryptophan enhances polyanion binding, extends lifetime, and reduces waste sensitivity.
Anna‐Lena Holtmannspötter +9 more
wiley +1 more source
Nano Biomedicine and EngineeringGraphene oxide (GO) and mesoporous silica nanoparticle (MSN) have been documented as advanced nanocarriers for drug delivery due to their unique and versatile properties.
Ketan B. Patil +3 more
doaj +1 more source
Primitive Membrane Formation, Characteristics and Roles in the Emergent Properties of a Protocell
Entropy, 2011 All contemporary living cells are composed of a collection of self-assembled molecular elements that by themselves are non-living but through the creation of a network exhibit the emergent properties of self-maintenance, self-reproduction, and evolution.
Pierre-Alain Monnard +1 more
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