Results 81 to 90 of about 3,765 (199)

Ion‐ and Temperature‐Programmable Reconfiguration of Subcompartments in Synthetic Cells

open access: yesChemBioChem, Volume 27, Issue 8, April 2026.
Spatial organization of subcompartments defines living cells, yet achieving dynamic and reversible compartmentalization remains challenging in bottom‐up synthetic cell design. We report a minimal, protein‐free mechanism in which Mg2+‐mediated intermembrane adhesion reversibly couples neutral large unilamellar vesicle (LUV) subcompartments to negatively
Zexi Xu, Petra Schwille
wiley   +1 more source

Investigating Prebiotic Protocells for a Comprehensive Understanding of the Origins of Life: A Prebiotic Systems Chemistry Perspective

open access: yesLife, 2019
Protocells are supramolecular systems commonly used for numerous applications, such as the formation of self-evolvable systems, in systems chemistry and synthetic biology.
Augustin Lopez, Michele Fiore
doaj   +1 more source

Protocell arrays for simultaneous detection of diverse analytes

open access: yesNature Communications, 2021
Simultaneous detection of multiple analytes from a sample is currently difficult. Here the authors present protocell arrays in a customisable platform integrating cell-free expression with a polymer-based aqueous two-phase system; they use this for ...
Yan Zhang   +5 more
doaj   +1 more source

SYNCHRONIZATION PHENOMENA IN PROTOCELL MODELS

open access: yesBIOMAT 2007, 2008
This work aims to consider simplified models of protocells in order to describe their general behaviors. The advantage of the modelling approach is that the early protocells of life-forms on Earth are not reproduced in the present time. However, the problem is considered as a right track to understand the origin of life as well as to work with more ...
FILISETTI, alessandro   +4 more
openaire   +4 more sources

Fast and Slow Signal Propagation in Abiotic Polypeptide Assemblies

open access: yesChemBioChem, Volume 27, Issue 6, 27 March 2026.
Proteinoid microspheres formed by thermal polymerization of amino acids exhibit spontaneous electrical potential fluctuations without genetic material, membranes, or ion channels. Multi‐electrode recordings and electron microscopy reveal composition‐dependent voltage oscillations, long‐term drifts, and correlated signals across electrodes.
Panagiotis Mougkogiannis   +1 more
wiley   +1 more source

Autopoiesis Concepts for Chemical Origins of Life and Synthetic Biology [Stenogram of the popular lecture on the foreign bibliographic seminar] [PDF]

open access: yes, 2017
The monograph (Luisi P.L. "The Emergence of Life: From Chemical Origins to Synthetic Biology", 2010, Cambridge University Press, Cambridge, New York etc., 315 p.) is a well-written, informative book providing a novel view on the interrelation between the
Gradoff, Olle
core  

A spatial model of autocatalytic reactions

open access: yes, 2010
Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs.
Alan J. McKane   +12 more
core   +2 more sources

Biomimetic Construction of Abiotic Membranes Through Acylation of Cationic Diamino Acids

open access: yesChemBioChem, Volume 27, Issue 6, 27 March 2026.
Cells produce membrane‐forming phospholipids through complex enzymatic pathways. Here, we present the in situ synthesis of a novel class of abiotic phospholipid analogs (APAs) featuring a permanent choline‐mimetic cation on diamino acid backbones.
Federica A. Souto‐Trinei   +2 more
wiley   +1 more source

Chemical systems, chemical contiguity and the emergence of life

open access: yesBeilstein Journal of Organic Chemistry, 2017
Charting the emergence of living cells from inanimate matter remains an intensely challenging scientific problem. The complexity of the biochemical machinery of cells with its exquisite intricacies hints at cells being the product of a long evolutionary ...
Terrence P. Kee, Pierre-Alain Monnard
doaj   +1 more source

The un-designability of the virtual. Design from problem-solving to problem-finding. [PDF]

open access: yes, 2018
Drawing on Gilles Deleuze (1991) this chapter investigates the virtual as what problematizes the possible by inserting contingency in the process of emergence of the new.
Marenko, Betti
core  

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