Results 31 to 40 of about 4,711 (225)
Fatty Acid Vesicles as Hard UV-C Shields for Early Life
Foundations, 2023 Theories on life’s origin generally acknowledge the advantage of a semi-permeable vesicle (protocell) for enhancing the chemical reaction–diffusion processes involved in abiogenesis.
Iván Lechuga, Karo Michaelian
doaj +1 more source
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]
, 2011 Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E +20 more
core +2 more sources
A stochastic model of catalytic reaction networks in protocells [PDF]
, 2014 Protocells are supposed to have played a key role in the self-organizing processes leading to the emergence of life. Existing models either (i) describe protocell architecture and dynamics, given the existence of sets of collectively self-replicating ...
Damiani, Chiara +5 more
core +1 more source
SURFACE-REACTION MODELS OF PROTOCELLS [PDF]
BIOMAT 2006, 2007 We present a class of models aiming to describe generic protocells hypotheses, improving a model introduced elsewhere[13]. These models, inspired by the 'Los Alamos bug' hypothesis, are composed by two coupled subsystems: a self-replicating molecule-SRM- and a lipid container.
SERRA, Roberto, T. CARLETTI, I. POLI
openaire +5 more sources
Designing with Protocells: Applications of a Novel Technical Platform
Life, 2014 The paper offers a design perspective on protocell applications and presents original research that characterizes the life-like qualities of the Bütschli dynamic droplet system, as a particular “species” of protocell.
Rachel Armstrong
doaj +1 more source
Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow
Life, 2014 Over the past few decades, several protocell models have been developed that mimic certain essential characteristics of living cells. These protocells tend to be highly reductionist simplifications of living cells with prominent bilayer membrane ...
Martin M Hanczyc
doaj +1 more source
Natural selection. III. Selection versus transmission and the levels of selection [PDF]
, 2011 George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission.
Frank, Steven A.
core +2 more sources
Progress in synthesizing protocells [PDF]
Experimental Biology and Medicine, 2018 The traditional route to investigating biology by perturbing living systems or by individually purifying and characterizing component parts is giving way to more complex endeavors where chemists and physicists attempt to build cells from scratch. Parallel efforts are underway that either exploits extant biological parts or prebiotically plausible ...
Toparlak, Omer Duhan, Mansy, Sheref S.
openaire +3 more sources
A Synthetic Protocell‐Based Heparin Scavenger [PDF]
Small, 2022 AbstractHeparin is a commonly applied blood anticoagulant agent in clinical use. After treatment, excess heparin needs to be removed to circumvent side effects and recover the blood‐clotting cascade. Most existing heparin antidotes rely on direct heparin binding and complexation, yet selective compartmentalization and sequestration of heparin would be ...
Yang, Shuo +6 more
openaire +6 more sources
Electrostatically gated membrane permeability in inorganic protocells [PDF]
, 2013 Although several strategies are now available to produce functional microcompartments analogous to primitive cell-like structures, little progress has been made in generating protocell constructs with self-controlled membrane permeability.
A Boker +30 more
core +4 more sources