Results 41 to 50 of about 4,711 (225)
Predatory behaviour in synthetic protocell communities [PDF]
, 2017 Recent progress in the chemical construction of colloidal objects comprising integrated biomimetic functions is paving the way towards rudimentary forms of artificial cell-like entities (protocells). Although several new types of protocells are currently
A Pohorille +40 more
core +4 more sources
Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis
Angewandte Chemie, EarlyView.Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han +7 more
wiley +2 more sources
Life, 2022 Although numerous reports using methods such as molecular dynamics, cellular automata, and artificial chemistry have clarified the process connecting non-life and life on protocell simulations, none of the models could simultaneously explain the ...
Takeshi Ishida
doaj +1 more source
Dynamic Transcription Machineries in Protocells. [PDF]
J Am Chem SocTranscription machineries play key roles in nature by regulating diverse cellular processes, including cell cycle progression, the control of intracellular metabolic balance, and cell differentiation and growth. These processes are regulated by the programmed transcription factor-mediated operation of transcription machineries and cellular ...
Dong J, Xia F, Huang F, Willner I.
europepmc +3 more sources
Effect of migration in a diffusion model for template coexistence in protocells [PDF]
, 2014 The compartmentalization of distinct templates in protocells and the exchange of templates between them (migration) are key elements of a modern scenario for prebiotic evolution.
Fontanari, Jose F., Serva, Maurizio
core +2 more sources
Angewandte Chemie, EarlyView.This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe +5 more
wiley +2 more sources
Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems
Life, 2019 In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the
Vismay Shah +4 more
doaj +1 more source
Protocells and RNA Self-Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The general notion of an "RNA world" is that, in the early development of life on the Earth, genetic continuity was assured by the replication of RNA, and RNA molecules were the chief agents of catalytic function. Assuming that all of the components of RNA were available in some prebiotic locale, these components could have assembled into activated ...
Gerald F. Joyce, Jack W. Szostak
openaire +2 more sources
Beilstein Journal of Organic Chemistry, 2017 Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss +2 more
doaj +1 more source
The Evolution of Active Droplets in Chemorobotic Platforms [PDF]
, 2017 There is great interest in oil-in-water droplets as simple systems that display astonishingly complex behaviours. Recently, we reported a chemorobotic platform capable of autonomously exploring and evolving the behaviours these droplets can exhibit.
Cronin, Lee +4 more
core +1 more source