Results 151 to 160 of about 5,052 (178)

Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing.

open access: yesJ Cell Sci
López-Cuevas P   +12 more
europepmc   +1 more source

Computing with Synthetic Protocells

Acta Biotheoretica, 2015
In this article we present a new kind of computing device that uses biochemical reactions networks as building blocks to implement logic gates. The architecture of a computing machine relies on these generic and composable building blocks, computation units, that can be used in multiple instances to perform complex boolean functions.
Courbet, Alexis   +2 more
openaire   +2 more sources

Modelling Protocells

2017
The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that
Roberto Serra, Marco Villani
openaire   +3 more sources

Toward Understanding Protocell Mechanosensation

Origins of Life and Evolution of Biospheres, 2010
Mechanosensitive (MS) channels can prevent bacterial bursting during hypo-osmotic shocks by responding to increases in lateral tension at the membrane level through an integrated and coordinated opening mechanism. Mechanical regulation in protocells could have been one of the first mechanisms to evolve in order to preserve their integrity against ...
openaire   +2 more sources

Protocells

2008
The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory.
openaire   +1 more source

Organic microstructures and terrestrial protocells

Naturwissenschaften, 1977
This letter concerns several issues in Folsome's recent paper on "Synthetic Organic Microstructnres and the Origins of Cellular Life" [1]. Thereismuch agreement [2, 3] that facile early formation of cell-like structures from (appropriate) nonbiological polymers is a crucial question [4]. However: 1.
Sidney W. Fox, Clair E. Folsome
openaire   +2 more sources

Protocell Research and Its Implications

Perspectives in Biology and Medicine, 2010
If and when protocells exist, they will exhibit three requisites for life: regeneration, replication, and evolution. Based on a recent collection of articles, this essay examines two major questions: (1) should research on development of protocells continue, and (2) what are the implications of this research for our understanding of "life."On the first
openaire   +2 more sources

Heterotrophic Model Protocells

2012
Heterotrophic model protocells are easier to build in the laboratory than autotrophic protocells. Advancements have shown that model heterotrophic systems can grow, divide, copy nucleic acids, and compete for resources. The required component molecules of the system are few and simple, in the sense that only a small number of monomeric species are ...
Del Bianco, Cristina   +1 more
openaire   +1 more source

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