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Protocells: Milestones and Recent Advances
Small, 2022 AbstractThe origin of life is still one of humankind's great mysteries. At the transition between nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain the structure and functions necessary to fulfill the criteria of life.
Irep Gözen +2 more
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The limits of metabolic heredity in protocells [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2022 The universal core of metabolism could have emerged from thermodynamically favoured prebiotic pathways at the origin of life. Starting with H 2 and CO 2 , the synthesis of amino acids and mixed fatty acids, which self-assemble into protocells, is ...
Raquel Nunes Palmeira +2 more
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A protocell with fusion and division
Biochemical Society Transactions, 2019A protocell is a synthetic form of cellular life that is constructed from phospholipid vesicles and used to understand the emergence of life from a nonliving chemical network. To be considered ‘living’, a protocell should be capable of self-proliferation, which includes successive growth and division processes.
Bo-Ying Xu, Jian Xu, Tetsuya Yomo
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Computing with Synthetic Protocells
Acta Biotheoretica, 2015In this article we present a new kind of computing device that uses biochemical reactions networks as building blocks to implement logic gates. The architecture of a computing machine relies on these generic and composable building blocks, computation units, that can be used in multiple instances to perform complex boolean functions.
Courbet, Alexis +2 more
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2017
The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that
Roberto Serra, Marco Villani
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The monograph discusses models of synthetic protocells, which are cell-like structures obtained from non-living matter endowed with some rudimentary kind of metabolism and genetics, but much simpler than biological cells. They should grow and proliferate, generating offsprings that resemble in some way the parent protocells with some variation, so that
Roberto Serra, Marco Villani
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2008
The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory.
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The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory.
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The chemical logic of a minimum protocell
Origins of life and evolution of the biosphere, 1988Traditional schemes for the origin of cellular life on earth generally suppose that the chance assembly of polymer synthesis systems was the initial event, followed by incorporation into a membrane-enclosed volume to form the earliest cells. Here we discuss an alternative system consisting of replicating membrane vesicles, which we define as minimum ...
H J, Morowitz, B, Heinz, D W, Deamer
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Computer Simulation of Protocells
2003When attempting to analyze, simulate and comprehend a vastly complex network such as a present-day living cell, one face enormous computing burden. Our group has in last decade worked on analyzing with similar methodologies the chemical behavior of much simpler systems, namely protocells.
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1997
Cellularization has the following main aspects that we have to explain: • The need for active (self-generated) compartmentation when metabolism is liberated from the surface. • The origin of membranogenic molecules and membranes. • The origin and mechanism of spontaneous protocell fission. • The transportation problem.
John Maynard Smith, Eors Szathmary
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Cellularization has the following main aspects that we have to explain: • The need for active (self-generated) compartmentation when metabolism is liberated from the surface. • The origin of membranogenic molecules and membranes. • The origin and mechanism of spontaneous protocell fission. • The transportation problem.
John Maynard Smith, Eors Szathmary
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2009
Experts explore the potential benefits, risks, and moral aspects of protocell technology, which creates simple forms of life from nonliving material. Teams of scientists around the world are racing to create protocells—microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials.
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Experts explore the potential benefits, risks, and moral aspects of protocell technology, which creates simple forms of life from nonliving material. Teams of scientists around the world are racing to create protocells—microscopic, self-organizing entities that spontaneously assemble from simple organic and inorganic materials.
openaire +1 more source