Results 1 to 10 of about 57,965 (293)

Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study

Critical Care Explorations, 2021
OBJECTIVES:. Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development.
Ami Shiddapur, BS, Christine E. Kistler, MD, MASc, Jan Busby-Whitehead, MD, C. Adrian Austin, MD, MSCR   +3 more
doaj   +1 more source

Regular proton pump inhibitor use and incident dementia: population-based cohort study

BMC Medicine, 2022
Background To examine the association between regular use of proton pump inhibitors and the risk of incident dementia, including dementia subtypes, and whether the association differs between APOE genotypes.
Peidong Zhang, Zhihao Li, Peiliang Chen, Ao Zhang, Yu Zeng, Xiru Zhang, Qingmei Huang, Dan Liu, Songtao Qi, Chen Mao   +9 more
doaj   +1 more source

Omeprazole-induced and pantoprazole-induced asymptomatic hyponatremia: a case report

Journal of Medical Case Reports, 2020
Background Hyponatremia is the most common electrolyte disorder. Thiazides, antidepressants, antipsychotic drugs, and antiepileptic drugs are well-known causes of hyponatremia. Proton pump inhibitor use is a rare cause of hyponatremia and, when reported,
Isabel J. B. van der Zalm, Tom J. M. Tobé, Susan J. J. Logtenberg   +2 more
doaj   +1 more source

Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]

PLoS ONE, 2018
BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee, Haekyung Lee, Song Hee Oh, Joonbyung Park, Suyeon Park, Jin Seok Jeon, HyunJin Noh, Dong Cheol Han, Soon Hyo Kwon   +8 more
doaj   +1 more source

Proton pump inhibitor deprescription: A rapid review [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
Proton pump inhibitors (PPI) are drugs that suppress gastric acid secretion. Its use, without support from scientific evidence, can contribute to polypharmacy, lead to drug interactions and, in the long term, cause serious adverse reactions.
Renata Rodriguez Imparato, Tereza Setsuko Toma   +1 more
doaj   +1 more source

Cost-utility analysis of imrecoxib compared with diclofenac for patients with osteoarthritis

Cost Effectiveness and Resource Allocation, 2021
Background To estimate the cost -utility of imrecoxib compared with diclofenac, as well as the addition of a proton pump inhibitor to both two treatment strategies, for patients with osteoarthritis, from a Chinese healthcare perspective. Methods A Markov
Xueshan Sun, Xuemei Zhen, Xiaoqian Hu, Yuanyuan Li, ShuYan Gu, Yuxuan Gu, Zixuan Zhao, Wei Yang, Hengjin Dong   +8 more
doaj   +1 more source

Relationship Between Long-Term Proton Pump Inhibitor Use and Serum Magnesium Levels: A Cross-Sectional Study

Life and Science, 2023
Objective: The objective of this study is to determine the effect of long-term proton pump inhibitor use on serum magnesium levels Study Design: Descriptive cross-sectional study.
Fuad Ahmad Siddiqi, Wasif Anwar, Muhammad Saad Aziz, Muhammad Hammad, Abdul Rehman Arshad, Umer Naseer   +5 more
doaj   +1 more source

Association between proton pump inhibitor use and risk of fracture: A population-based case-control study.

PLoS ONE, 2020
ObjectivesThe purpose of this study was to reconfirm the association between the risk of fracture and proton pump inhibitor use and to establish evidence for defining a high-risk group of patients among proton pump inhibitor users.MethodsA nested case ...
Jong Joo Kim, Eun Jin Jang, Jiwon Park, Hyun Soon Sohn   +3 more
doaj   +1 more source

Iron deficiency anemia from iron malabsorption caused by proton pump inhibitors

eJHaem, 2020
Background Iron deficiency anemia without evidence for blood loss can present a diagnostic challenge. Proton pump inhibitors have been associated with iron deficiency anemia for many years, yet the relationship between the two until recently was not ...
Michael Boxer
doaj   +1 more source

Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy

BMC Gastroenterology, 2012
Background High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy.
Yen Hsu-Heng, Yang Chia-Wei, Su Wei-Wen, Soon Maw-Soan, Wu Shun-Sheng, Lin Hwai-Jeng   +5 more
doaj   +1 more source