Results 41 to 50 of about 108,225 (293)

Risk of Bacterial Infection from Proton Pump Inhibitor Use

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017
Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim, Yunju Jo, Seun Ja Park, Jeong Seop Moon, Dong Ho Lee, Jae Jun Kim, Yong Chan Lee, Ethics and Education Committee of Korean College of Helicobacter and Upper Gastrointestinal Research   +7 more
doaj   +1 more source

Efficacy of Helicobacter pylori eradication therapies: a single centre observational study

BMC Gastroenterology, 2001
Background Many Helicobacter pylori eradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The overall results of eradication therapy in a cohort of patients are described and
Beales Ian LP
doaj   +1 more source

Proton pump inhibitors and the risk of pneumonia: A comparison of cohort and self-controlled case series designs [PDF]

, 2013
Background: To compare the results of a new-user cohort study design and the self-controlled case series (SCCS) design using the risk of hospitalisation for pneumonia in those dispensed proton pump inhibitors compared to those unexposed as a case study ...
Australian Bureau of Statistics (ABS), C Farrington, C Farrington, C-S Eom, CP Farrington, DA Zink, Elizabeth E Roughead, Emmae N Ramsay, HJ Whitaker, HJ Whitaker, J Glanz, J Hippisley-Cox, KL Sloan, L Thomas, Nicole L Pratt, Philip Ryan, R Laheij, RJ Laheij, S Gulmez, S Suissa, S Suissa, SE Gulmez, SV Gadzhanova   +22 more
core   +1 more source

Proton pump inhibitors overuse - consequences among patients

Journal of Education, Health and Sport, 2019
Introduction Omeprazole was first proton pump inhibitor (PPI) approved for use by patients. Thirty years have passed since then. Due to their effectiveness, low price and safety proton pump inhibitors have become one of the most frequently prescribed ...
Patrycja Kmiotek, Andrzej Materniak, Barbara Skrzydło-Radomańska   +2 more
doaj   +3 more sources

Eradication of Helicobacter Pylori

Медицинский совет, 2015
General idea. The article is a review of data on Helicobacter pylori resistance to antibiotics, the impact of CYP2C19 polymorphism on the metabolism of proton pump inhibitors, and recent findings on the effectiveness of eradication.
V. V. Tsukanov, E. V. Kasparov, A. V. Vasyutin, Y. L. Tonkikh   +3 more
doaj   +1 more source

Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]

, 2019
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
core   +2 more sources

Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]

, 2006
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko, Erdeljić, Viktorija, Francetić, Igor, Huić, Mirjana, Macolić Šarinić, Viola, Makar-Aušperger, Ksenija, Merčep, Iveta   +6 more
core   +1 more source

The relationship between long-term use of proton pump inhibitor (PPI) and hypomagnesemia in patients with gastroesophageal reflux disease

Caspian Journal of Internal Medicine, 2022
Background: The aim of this study was to evaluate the relationship between the long-term use of PPI and hypomagnesemia in patients with gastroesophageal reflux disease. Methods: This case control study was conducted on GERD patients with long-term use of
Abbas Arj, Zeinab Ghaletakizadeh, Hamidreza Gilassi, Mohsen Razavizadeh   +3 more
doaj  

Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study

Trials, 2018
Background Proton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit.
Joerg C. Schefold, Anders Perner, Theis Lange, Jørn Wetterslev, Matt P. Wise, Mark Borthwick, Stepani Bendel, Frederik Keus, Anne Berit Guttormsen, Søren Marker, Mette Krag, Morten Hylander Møller, for the SUP-ICU investigators   +12 more
doaj   +1 more source

Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory. [PDF]

, 2019
Proton-pump inhibitors, PPIs, are considered effective therapy for stomach acid suppression due to their irreversible inhibition of the hydrogen/potassium pump in the gastric parietal cells. They are widely prescribed and are considered safe for over-the-
Abagyan, Ruben, Alpatty, Sama, Atayee, Rabia S, Lee, Kelly C, Makunts, Tigran   +4 more
core   +1 more source