Results 71 to 80 of about 117,037 (362)
Proton Pump Inhibitors: Are They a Real Threat to the Patient?
GE: Portuguese Journal of Gastroenterology, 2018 Background: Proton pump inhibitors are among the most frequently prescribed drugs in the world and are generally considered safe. However, there is growing concern regarding their safety.
Sofia Xavier +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source
Nepalese Medical Journal, 2019 Introduction: Endoscopic band ligation is the mainstay of treatment in bleeding varices in cirrhosis. Subsequent bleeding from the band ulcers is a possible complication.
Binod Karki +9 more
doaj +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
Advanced Functional Materials, EarlyView.This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer +10 more
wiley +1 more source
An Exploratory Analysis of Pharmaceutical Price Disparities and Their Implications Among Six Developed Nations [PDF]
, 2006 In our study of 43 drugs, prescription drug prices in several wealthy nations (Australia, Canada, France, Germany, and the U.K.) were much lower than in the U.S. on average, well below relative per capita GDP. There was relatively little difference among
Elizabeth DuPre +2 more
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Efficacy of Adding Baclofen to Treat Patients with Non-Erosive Reflux Disease Resistant to Treatment
مجله دانشکده پزشکی اصفهان, 2015 Background: Non-erosive reflux disease (NERD) is one of the categories of gastro-esophageal reflux disease defined as the presence of classic reflux symptoms in the absence of esophageal mucosal injury during upper endoscopy.
Mahsa Foroughi +2 more
doaj
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Advanced Functional Materials, EarlyView.Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh +3 more
wiley +1 more source
Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease [PDF]
, 2019 A new paradigm for Niemann-Pick C disease is presented where lysosomal storage leads to a deficit in cytoplasmic glucosylceramide (GlcCer) where it performs important functions.
Bhardwaj, Meenakshi +5 more
core +1 more source
Transforming Cellulose Into Functional Three‐Dimensional Structures
Advanced Functional Materials, EarlyView.Cellulose is promising for replacing synthetic polymers due to its excellent mechanical properties and low cost. This review highlights the recent advancements in transforming cellulose into functional 3D structures, including liquid gels and porous materials.
Xia Sun +5 more
wiley +1 more source
The benefits--and limits-- of PPIs with warfarin regimens [PDF]
, 2017 Patients on warfarin + antiplatelet/NSAID regimens are likely to benefit from the gastroprotective effect of PPIs. For patients taking warfarin alone, it's a different story.
Ludden-Schlatter, Alicia +1 more
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