Results 1 to 10 of about 7,756 (192)

The Importance of Vacuolar Ion Homeostasis and Trafficking in Hyphal Development and Virulence in Candida albicans

Frontiers in Microbiology, 2021
The vacuole of Candida albicans plays a significant role in many processes including homeostasis control, cellular trafficking, dimorphic switching, and stress tolerance.
Quanzhen Lv, Lan Yan, Yuanying Jiang
doaj   +1 more source

Evolutionary primacy of sodium bioenergetics

Biology Direct, 2008
Background The F- and V-type ATPases are rotary molecular machines that couple translocation of protons or sodium ions across the membrane to the synthesis or hydrolysis of ATP.
Wolf Yuri I, Makarova Kira S, Galperin Michael Y, Mulkidjanian Armen Y, Koonin Eugene V   +4 more
doaj   +1 more source

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn, Alexandersson, Armengaud, Banuelos, Benschop, Brugiere, Carter, Chrispeels, Ducos, Dunkley, Endler, Gaxiola, Gierth, Jacquinod, Komatsu, Larsson, Loque, Lüttge, Ma, Maathuis, Maathuis, Marmagne, Morsomme, Niittyla, Nühse, Nühse, Paszkowski, Peltier, Pighin, Rentsch, Sancenon, Tanaka, Tornroth-Horsefield, Toyofuku, Vitart, Whiteman, Wintz, Wu, Yazaki   +38 more
core   +1 more source

Understanding the apparent stator-rotor connections in the rotary ATPase family using coarse-grained computer modeling [PDF]

, 2014
Advances in structural biology, such as cryo-electron microscopy (cryo-EM) have allowed for a number of sophisticated protein complexes to be characterized.
Balakrishna, Benlekbir, Bernal, Bottcher, Boyer, Chacon, Cherepanov, Fischer, Grabe, Imamura, Junge, Kane, Lau, Lau, Matthies, Meier, Meyer, Mitome, Muench, Muench, Muench, Noji, Oliver, Pogoryelov, Pogoryelov, Quillin, Radmacher, Sambongi, Schöberl, Sielaff, Song, Stember, Stewart, Sumner, Tabke, Tama, Tirion, Vollmar, Wachter, Wriggers, Yokoyama   +40 more
core   +1 more source

The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery

Cell Reports, 2017
Vacuolar H+-ATPase (v-ATPase) is a multi-subunit complex comprising two domains: the cytosolic V1 domain catalyzing ATP hydrolysis and the membranous V0 sector translocating protons across membranes.
Anna Bodzęta, Martin Kahms, Jürgen Klingauf   +2 more
doaj   +1 more source

Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer [PDF]

, 2012
Cancer cells show a metabolic shift that makes them overproduce protons; this has the potential to disturb the cellular acid-base homeostasis. However, these cells show cytoplasmic alkalinisation, increased acid
Hernández López, Agustín, Pérez Castiñeira, José Román, Serrano Bueno, Gloria, Serrano Delgado, Aurelio   +3 more
core   +1 more source

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

eLife, 2016
A molecular model that provides a framework for interpreting the wealth of functional information obtained on the E. coli F-ATP synthase has been generated using cryo-electron microscopy.
Meghna Sobti, Callum Smits, Andrew SW Wong, Robert Ishmukhametov, Daniela Stock, Sara Sandin, Alastair G Stewart   +6 more
doaj   +1 more source

Cryo-EM studies of the rotary H+-ATPase/synthase from Thermus thermophilus

Biophysics and Physicobiology, 2019
Proton-translocating rotary ATPases couple proton influx across the membrane domain and ATP hydrolysis/synthesis in the soluble domain through rotation of the central rotor axis against the surrounding peripheral stator apparatus.
Atsuko Nakanishi, Jun-ichi Kishikawa, Kaoru Mitsuoka, Ken Yokoyama   +3 more
doaj   +1 more source

Estimating the Rotation Rate in the Vacuolar Proton-ATPase in Native Yeast Vacuolar Membranes [PDF]

, 2012
The rate of rotation of the rotor of the yeast vacuolar proton-ATPase (V-ATPase), relative to the stator or the steady parts of enzyme, is estimated in native vacuolar membrane vesicles of Saccharomyces cerevisiae under standardised conditions.
Bóta, A., Dér, A., Ferencz, C., Fodor-Ayaydin, E., Haracska, L., Kóta, Z., Marsh, D., Petrovszki, P., Páli, T., Varga, Z.   +9 more
core   +1 more source

A deeply branching thermophilic bacterium with an ancient acetyl-CoA pathway dominates a subsurface ecosystem [PDF]

, 2012
A nearly complete genome sequence of Candidatus ‘Acetothermum autotrophicum’, a presently uncultivated bacterium in candidate division OP1, was revealed by metagenomic analysis of a subsurface thermophilic microbial mat community.
A Stamatakis, A Teske, AK Kaster, AL Brioukhanov, Atsushi Toyoda, AY Mulkidjanian, B Boussau, D Wu, DJ Tobler, DS Kelley, E Biegel, E Biegel, E Pierce, EF DeLong, EG Nisbert, F Nikitin, FD Ciccarelli, G Proskurowski, G Wächtershäuser, Gab-Joo Chee, H Hirayama, H Kimura, H Noguchi, H Takami, H Takami, H Takami, Hideki Noguchi, Hideto Takami, I Uchiyama, I Uchiyama, Ikuo Uchiyama, JA Baross, Jack Anthony Gilbert, JB Corliss, JR Torre, K Takai, K Takai, K Takai, KC Costa, Ken Takai, M Toei, M Wu, M Wu, Masahira Hattori, MB Scott, MS Rappé, N Saitou, O White, P Hugenholtz, R Caspi, R Chenna, RF Say, RT Thauer, S Guindon, S Kato, Shinro Nishi, T Murata, T Nunoura, T Nunoura, T Sakiyama, T Shibuya, Takehiko Itoh, Takuro Nunoura, TM Lowe, V Müller, W Martin, W Martin, W Martin, Wataru Arai, Yoshihiro Takaki   +69 more
core   +8 more sources