Results 21 to 30 of about 5,151 (179)

Cryo-EM studies of the rotary H+-ATPase/synthase from Thermus thermophilus

Biophysics and Physicobiology, 2019
Proton-translocating rotary ATPases couple proton influx across the membrane domain and ATP hydrolysis/synthesis in the soluble domain through rotation of the central rotor axis against the surrounding peripheral stator apparatus.
Atsuko Nakanishi, Jun-ichi Kishikawa, Kaoru Mitsuoka, Ken Yokoyama   +3 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The assignment of the Ca²⁺‐ATPase activity of chromaffin granules to the proton translocating ATPase [PDF]

FEBS Letters, 1985
Ca2+‐ATPase H+‐ATPase Proton pump Chromaffin granule Adrenal medulla
Sissel Vik Berge, Eystein S. Husebye, Martin Grønberg, Torgeir Flatmark   +3 more
openaire   +3 more sources

Proton-translocating ATPase and lysosomal cystine transport.

Journal of Biological Chemistry, 1983
A proton-translocating ATPase was identified in highly purified lysosomes from Epstein-Barr virus-transformed human lymphoblasts. Activity of this ATPase caused acidification of highly purified, fluorescein isothiocyanate dextran-loaded lysosomes and correlated with the ATP-dependent efflux of lysosomal cystine.
Jerry A. Schneider, W S Allison, Alice A. Greene, Adam J. Jonas, P K Laikind, Margaret L. Smith   +5 more
openaire   +3 more sources

Effect of antihypertensive agents - captopril and nifedipine - on the functional properties of rat heart mitochondria [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): Investigation of acute effect on cellular bioenergetics provides the opportunity to characterize the possible adverse effects of drugs more comprehensively.
Ivana Kancirová, Magdaléna Jašová, Iveta Waczulíková, Táňa Ravingerová, Attila Ziegelhöffer, Miroslav Ferko   +5 more
doaj  

Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli [PDF]

Journal of Bacteriology, 1982
We investigated the regulation of the synthesis of the eight polypeptides of the Escherichia coli proton-translocating ATPase. A plasmid carrying the eight genes of the unc operon was used to direct in vivo and in vitro protein synthesis of the eight polypeptides.
W S Brusilow, R. D. Simoni, Daniel J. Klionsky   +2 more
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Topology of the Yeast Plasma Membrane Proton-translocating ATPase

Journal of Biological Chemistry, 1989
Four proteases have been used to assess the topology of the H+-ATPase from Saccharomyces cerevisiae reconstituted into phosphatidylserine vesicles. Limited proteolysis by trypsin and alpha-chymotrypsin inactivates the enzyme and produces stable, membrane-bound fragments. Sequence analyses of these peptides have located the peptide bonds hydrolyzed. The
Charles B. Davis, Gordon G. Hammes
openaire   +3 more sources