Results 121 to 130 of about 3,306,946 (213)

Impact of Relative Biologic Effectiveness for Proton Therapy for Head and Neck and Skull-Base Tumors: A Technical and Clinical Review

Proton therapy has emerged as a crucial tool in the treatment of head and neck and skull-base cancers, offering advantages over photon therapy in terms of decreasing integral dose and reducing acute and late toxicities, such as dysgeusia, feeding tube ...
Lisa A. McGee, David M. Routman, Adam L. Holtzman, Daniel M. Koffler, Scott C. Lester, Homan Mohammadi, Mauricio E. Gamez, Keith M. Furutani, Chris J. Beltran, Xiaoying Liang   +9 more
core   +1 more source

Towards proton arc therapy: physical and biologically equivalent doses with increasing number of beams in pediatric brain irradiation

, 2019
Background: Proton arc therapy may improve physical dose conformity and reduce concerns of elevated linear energy transfer (LET) and relative biological effectiveness (RBE) at the end of the proton range, while offering more degrees of freedom for normal
Camilla H. Stokkevåg (7534082), Jørgen B. B. Petersen (7534079), Oscar Casares-Magaz (815704), Daniel J. Indelicato (7534076), Yasmin Lassen-Ramshad (722028), Anne Vestergaard (810458), Katrine S. Holgersen (6952817), Laura Toussaint (6914414), Ludvig P. Muren (7534085)   +8 more
core   +1 more source

Cross-modality Dosimetry Audit in Head-and-neck Radiotherapy: A Phantom-based Approach for Photon and Proton Beams

Journal of Medical Physics
Purpose: The purpose of this study was to implement and evaluate an end-to-end (E2E) test using an anthropomorphic head-and-neck (H and N) phantom across different radiotherapy modality platforms for photon and proton.
Sornjarod Oonsiri, Sakda Kingkaew, Mananchaya Vimolnoch, Nichakan Chatchumnan, Puntiwa Oonsiri   +4 more
doaj   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

Advanced NanoBiomed Research, Volume 6, Issue 11, November 2026.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang, Liwei Liu, Jiayuan Zhu, Xinghao Hu, Changkui Fu, Yao Wang, Lining Arnold Ju, Thomas P. Davis, Andriansjah Rukmana, Shaohua Ma, Zheng Zhang, Ruirui Qiao   +11 more
wiley   +1 more source

Photon and proton therapy planning comparison for malignant glioma based on CT, FDG-PET, DTI-MRI and fiber tracking

, 2011
The purpose of this study was to compare treatment plans generated using fixed beam Intensity Modulated photon Radiation Therapy (IMRT), inversely optimized arc therapy (RapidArc(R), RA) with spot-scanned Intensity Modulated Proton Therapy (IMPT) for ...
Silke Engelholm, Munck af Rosenschöld, Per, Law, Ian, Ian Law, Per Munck af Rosenschöld, Vogelius, Ivan, Lars Ohlhues, Engelholm, Silke, Ohlhues, Lars, Ivan Vogelius, Engelholm, Svend Aage, Svend Aage Engelholm   +11 more
core   +1 more source

Volumetric Modulated Arc Therapy Craniospinal Irradiation Utilizing a Vertebral Body Sparing Approach: An Alternative Approach to Improve Access and Minimize Toxicity

Advances in Radiation Oncology
Introduction: Craniospinal irradiation (CSI) is indicated for adult patients diagnosed with leptomeningeal disease (LMD). Proton-based vertebral body sparing (VBS) CSI has been explored with pediatric patients to minimize hematologic toxicity; however ...
Haley K. Perlow, MD, Jennifer K. Matsui, PhD, Ashlee Ewing, CMD, Catherine Cadieux, CMD, Khaled Dibs, MBBS, Rituraj Upadhyay, MD, Dukagjin M. Blakaj, MD, PhD, Sasha J. Beyer, MD, PhD, Evan M. Thomas, MD, PhD, John C. Grecula, MD, Raju R. Raval, MD, DPhil, Joshua D. Palmer, MD   +11 more
doaj   +1 more source

Preparation, Spectroscopic Elucidation, Antioxidant Potential, Enzyme Inhibition, and Molecular Docking Studies of Novel Schiff Base‐Derived Thiosemicarbazones

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
The synthesis of new thiosemicarbazones bearing Schiff base was performed. The structures of the compounds were characterized through several spectroscopic methods. The antioxidant potential of these compounds was evaluated through DPPH• in vitro assays. In addition, their inhibitory activities against urease and xanthine oxidase (XO) were investigated.
Hasan Yakan, Halit Muglu, Semiha Yenigun, Tevfik Ozen   +3 more
wiley   +1 more source

PAMELA : overview and status [PDF]

, 2010
The status of the PAMELA (Particle Accelerator for MEdical Applications) project to design an accelerator for proton and light ion therapy using non-scaling Fixed Field Alternating Gradient (ns-FFAG) accelerators is reviewed and ...
Easton, M.J., Tzenov, S.I., Pasternak, J., Witte, H., Johnstone, C., Edgecock, T. R., Machida, S., Cobb, J., Barlow, R. J., Fenning, R.J.L., Vojnovic, B., Owen, H. L., Pattalwar, S., Jones, B., Yokoi, T., Tygier, S.C., Gardner, I.S.K., Witte, H, Hill, M.A., Beard, Carl, Peach, K., Fenning, R., Hill, M., Khan, A., McIntosh, P.A., Bliss, N., Seviour, R., Tygier, S., Edgecock, R., Kelliher, D.J., Tzenov, S., Jones, T.J., Cobb, J H, Smith, S. L., Peach, K. J., Kelliher, D., Pattalwar, S.M., Barlow, Roger, Sheehy, S. L., Aslaninejad, M., Easton, M., Beard, C.D., Pozimski, J.K., Owen, H., Gardner, I. S K, Seviour, Rebecca, Strachan, J., McIntosh, P., Pozimski, Jürgen Klaus, Smith, S.L., Jones, T.   +50 more
core   +1 more source

Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Photon radiotherapy, typically volumetric modulated arc therapy (VMAT), is the standard for adjuvant or definitive treatment of vulvar cancer.
Anna C. Prins, Raymond de Boer, András G. Zolnay, Remi A. Nout, Mischa S. Hoogeman, Kelvin Ng Wei Siang   +5 more
doaj   +1 more source

Optimizing the traversal time for gantry trajectories for proton arc therapy treatment plans

Physics in Medicine & Biology
Abstract Background. Proton arc therapy (PAT) is an emerging radiation therapy technique where either the gantry or the patient continuously rotates during the irradiation treatment. One of the perceived advantages of PAT is the reduced treatment time, but it is still unclear exactly how long ...
Wase, Viktor, Marthin, Otte, Fredriksson, Albin, Finnson, Anton   +3 more
openaire   +3 more sources