Results 141 to 150 of about 3,306,946 (213)

Biological Effectiveness of Intensity-Modulated Proton Therapy and Proton Arc Therapy

Purpose: Proton therapy offers precise tumor targeting with minimal radiation to healthy tissue, making it especially valuable for treating pediatric patients with brain tumors. Proton Arc Therapy (PAT) takes this a step further by delivering the dose along a continuous arc around the patient, as opposed to the fewer fields used in Intensity-Modulated ...
openaire   +1 more source

Is proton beam therapy always better than photon irradiation? Lessons from two cases

Journal of Medical Radiation Sciences
Proton beam therapy (PBT) is increasingly used to treat cancers, especially in the paediatric and adolescent and young adult (AYA) population. As PBT becomes more accessible, determining when PBT should be used instead of photon irradiation can be ...
Michelle P Li, Adam Yeo, Roshini Gunewardena, Gabrielle Drum, Kirsty Wiltshire, Claire Phillips, Joseph Sia, Greg Wheeler, Lisa Hall   +8 more
doaj   +1 more source

PAMELA Overview : design goals and principles [PDF]

, 2009
The PAMELA (Particle Accelerator for MEdicaL Applications) project is to design an accelerator for proton and light ion therapy using non-scaling Fixed Field Alternating Gradient (FFAG) accelerators, as part of the CONFORM project, which is also ...
Easton, M.J., Tzenov, S.I., Khan, A., Pasternak, J., McIntosh, P.A., Witte, H., Johnstone, C., Bliss, N., Machida, S., Edgecock, R., Kelliher, D.J., Rogers, C.T., Peach, K. J., Owen, H.L., Fenning, R.J.L., Vojnovic, B., Barlow, Roger, Sheehy, S. L., Aslaninejad, M., Jones, B., Yokoi, T., Tygier, S.C., Beard, C.D., Pozimski, J.K., Seviour, Rebecca, Rochford, J., Cobb, J.H., Smith, S.L.   +27 more
core  

Evolving role of proton therapy in contemporary oncology [PDF]

Cancer
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Lebow E, Shih H.
europepmc   +2 more sources

Treatment planning comparison for head and neck cancer between photon, proton, and combined proton-photon therapy - from a fixed beam line to an arc.

BACKGROUND AND PURPOSE This study investigates whether combined proton-photon therapy (CPPT) improves treatment plan quality compared to single-modality intensity-modulated radiation therapy (IMRT) or intensity-modulated proton therapy (IMPT) for head ...
Bachtiary, Barbara, Weber, Damien Charles, Lomax, Antony J, Zhang, Ye, Amstutz, Florian, Krcek, Reinhardt, Unkelbach, Jan   +6 more
core   +1 more source

A treatment plan optimization method with direct minimization of number of energy jumps for proton arc therapy. [PDF]

Phys Med Biol, 2023
Zhang G, Long Y, Lin Y, Chen RC, Gao H.
europepmc   +1 more source

A critical appraisal of the clinical utility of proton therapy in oncology

, 2015
Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients.
Wang D
core  

Machine Model-Specific Delivery Sequence Optimization for Spot-scanning Proton Arc Therapy Using a Compact Superconducting Synchrocyclotron. [PDF]

Med Phys
Liu P, Zhao L, Cong X, Liu G, Li X, Ding X.   +5 more
europepmc   +1 more source

Reducing the dose delivered to major intracranial blood vessels in brain radiotherapy using spot-scanning proton arc therapy. [PDF]

J Appl Clin Med Phys
Liu P, Tattenberg S, Cong X, Chen PY, Ding X, Hammi A.   +5 more
europepmc   +1 more source

Comparison of in-field secondary cancer risk based on therapeutic proton dose between proton arc therapy and intensity-modulated proton therapy in lung cancer patients. [PDF]

J Appl Clin Med Phys
Xu Y, Chen W, Wu J, Guo H, Zeng F, Zhang T, Yang F, Huang X, Zhang D, Wang X.   +9 more
europepmc   +1 more source