Results 131 to 140 of about 3,306,946 (213)

Applying Proteogenomics to Characterize Molecular Features Associated With a High‐Risk HOXB13 Gene Variant in Prostate Cancer Tumors

MedComm, Volume 7, Issue 11, November 2026.
Prostate tumors from six heterozygous G84E variant carriers (G84E positive) and 18 non‐carriers (wild‐type) were examined using the Human AmpliSeq Transcriptome Gene Expression Panel, and proteomes were generated by mass spectrometry (SWATH). We identified a 799‐gene expression profile and a 75‐protein expression profile in G84E‐positive tumors when ...
Kelsie Raspin, Zainab Noor, Adel T. Aref, James R. Marthick, Chol‐hee Jung, Shaun Donovan, Steve Williams, Peter G. Hains, Phillip J. Robinson, Rosemary L. Balleine, Qing Zhong, Roger R. Reddel, Liesel M. FitzGerald, Joanne L. Dickinson   +13 more
wiley   +1 more source

Dosimetric Advantage of Scanning Beam Proton Therapy in Gynecologic Patients Receiving Adjuvant Radiotherapy

Background/Objectives: Adjuvant radiation for gynecologic malignancies often exposes organs at risk (OARs), such as the bone marrow, bowel, rectum, and bladder, to radiation, leading to toxicities that impact treatment tolerance and patient quality of ...
Ger, Rachel B, Lemish, Pamela R, Bues, Martin, Justin D. Anderson, Christopher J. Kutyreff, Ridgway, Ana K, Christie A. Schulz, Pedro R. Lara, Anand, Aman, Martin Bues, Danairis Hernandez Morales, Niedzielski, Joshua S, Kutyreff, Christopher J, Rachel B. Ger, Aman Anand, Justin D. Gagneur, Lara, Pedro R, Vora, Sujay A, Schulz, Christie A, Joshua S. Niedzielski, Pamela R. Lemish, Ana K. Ridgway, Jarrod M. Lentz, Sujay A. Vora, Hernandez Morales, Danairis, Gagneur, Justin D, Lentz, Jarrod M, Anderson, Justin D   +27 more
core   +1 more source

Pitfalls in diagnosing and long‐term management of ceroid lipofuscinosis NCL4A in a mixed‐breed dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐year‐old, spayed, female, mixed‐breed dog was presented with a 9‐month history of occasionally stumbling on walks, having difficulty navigating stairs and jumping into the car. A prior computed tomography scan of the head revealed mild leptomeningeal enhancement and suggested meningoencephalitis.
Ingeborg Hein, Ines Heinreich, Florian Willmitzer, Marion Mucha   +3 more
wiley   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1219-1233, November 2026.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala, Sameer Rao, Manas Gunani, Kajol Shah, Anand V. Kulkarni, Karn Wijarnpreecha, Daniel Q. Huang, Pojsakorn Danpanichkul, Ahmed Al‐Khazraji, Kaveh Hajifathalian, Vivek Lingiah, Paul Gaglio, Nikki Duong, Christine Gerula   +13 more
wiley   +1 more source

Robustness assessment using probabilistic scenarios of intensity modulated proton therapy and volumetric arc therapy in non-small-cell lung cancer: an in-silico radiotherapy planning study

, 2017
Radiotherapy is an essential treatment component for patients with stage III non-small-cell lung cancer. Despite advances, survival remains poor. Proton beam therapy holds the promise of improving cure rates without increasing treatment-related toxicity.
Van den Heuvel, Frank, Fiorini, Francesca, George, Ben, Teoh, Suliana, Vallis, Katherine   +4 more
core  

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1184-1196, November 2026.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Investigation of the DSF/Cu Reaction Using HR LCMS and Reactivity Studies

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
The generation of Cu(II)bis(diethyldithiocarbamate) from the combination of disulfiram and Cu salts, as used in many cuprototic cancer studies, is examined using high‐resolution liquid chromatography‐mass spectroscopy. By monitoring the reaction at different sampling times to determine reaction intermediates and the addition of adduct‐forming traps, a ...
Jordan Lyons, Patrick J. Farmer
wiley   +1 more source

Robustness assessment using probabilistic scenarios of intensity modulated proton therapy and volumetric arc therapy in non-small-cell lung cancer: an in-silico radiotherapy planning study

, 2018
Radiotherapy is an essential treatment component for patients with stage III non-small-cell lung cancer. Despite advances, survival remains poor. Proton beam therapy holds the promise of improving cure rates without increasing treatment-related toxicity.

core  

Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma. [PDF]

J Appl Clin Med Phys, 2023
Cao W, Li Y, Zhang X, Poenisch F, Yepes P, Sahoo N, Grosshans D, McGovern S, Gunn GB, Frank SJ, Zhu XR.   +10 more
europepmc   +1 more source

Encapsulation of Porphyrins in Polymer Microgels and Microbeads for Heterogeneous Photooxidation

ChemSusChem, Volume 19, Issue 19, 14 October 2026.
Amino‐ or ammonium‐functionalized tetraphenylporphyrins were synthesized and encapsulated within polymers to form microgels and microbeads that act as heterogeneous photocatalysts. Photooxidation in aqueous media quantitatively converts sulfides and aldehydes into sulfoxides and carboxylic acids via the singlet‐oxygen pathway, demonstrating an ...
Imogen Smith, Natthakarn Olanchantarothai, Martin R. Johnston, Zhongfan Jia   +3 more
wiley   +1 more source