Results 221 to 230 of about 108,823 (265)

Cytochrome oxidase as a proton pump

Journal of Bioenergetics and Biomembranes, 1991
The general structure of cytochrome oxidase is reviewed and evidence that the enzyme acts as a redox-linked proton pump outlined. The overall H+/e- stoichiometry of the pump is discussed and results [Wikström (1989), Nature 338, 293] which suggest that only the final two electrons which reduce the peroxide adduct to water are coupled to protein ...
M T, Wilson, D, Bickar
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Proton Pumping P Systems

2004
We propose here a (biologically inspired) model of P system called proton pumping P system that is a special case of evolution–communication P system. In cell biology there are transport mechanisms, involving protons. We generalize this idea by considering a few different types of protons.
Artiom Alhazov, Matteo Cavaliere
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Proton Pump Inhibitors for Dyspepsia

Digestive Diseases, 2008
Proton pump inhibitors are widely used in many upper gastrointestinal disorders. Dyspepsia is a common problem in primary care and endoscopy is neither feasible nor affordable in the majority of patients. <i>Helicobacter pylori</i> eradication has been shown to be effective, but with the declining prevalence of <i>H.
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Proton pump inhibitors

BMJ, 2023
Danny, Jenkins, Ines, Modolell
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Pantoprazole, Prout and the proton pump

Hospital Medicine, 1999
Pantoprazole is a proton pump inhibitor which has recently had its clinical license extended to include maintenance therapy for the treatment of reflux oesophagitis, Helicobacter pylori eradication and short-term intravenous administration. This article reviews the history of gastric acid secretion and examines the role of proton pump inhibitors ...
R J, Playford, T, Podas, I, Modlin
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Proton Pump Inhibitors

Annals of Pharmacotherapy, 2016
Objective: The purpose of this article is to describe the relationship between proton pump inhibitors (PPIs) and symptoms of myopathy based on case reports. Data Sources: A literature search was conducted in PubMed (1946 to June 2016) using MeSH terms proton pump inhibitors, omeprazole, esomeprazole, lansoprazole, dexlansoprazole, rabeprazole ...
Evan W, Colmenares, Ashley L, Pappas
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Proton pump inhibitors and osteoporosis

Current Opinion in Rheumatology, 2016
Purpose of review The purpose of the review is to provide an update on recent advances in the evidence based on proton pump inhibitors (PPI) as a possible cause of osteoporosis and osteoporotic fractures. This review focuses, in particular, on new studies published in the last 18 months and a discussion of these findings and ...
Andersen, Bjarne Nesgaard, Johansen, Per Birger, Abrahamsen, Bo   +2 more
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Bacteriorhodopsin as a model for proton pumps

Nature, 1995
According to a long-standing hypothesis, membrane pumps function by flip-flopping between two protein conformations that allow alternative access of the ion binding site to the two membrane surfaces. Site-specific mutagenesis, time-resolved spectroscopy and X-ray diffraction confirm this mechanism for bacteriorhodopsin, and implicate change of ...
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Proton Pump Caught in the Act

Science, 1999
How does a protein pump protons in only one direction? In his Perspective, Gennis explains how this occurs in bacteriorhodopsin, a membrane protein that pumps protons in response to light stimulation. A new structure by Luecke et al. on p.
R B, Gennis, T G, Ebrey
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Lansoprazole: A Proton Pump Inhibitor

Annals of Pharmacotherapy, 1996
OBJECTIVE: To summarize the published data on lansoprazole, a proton pump inhibitor approved by the Food and Drug Administration for use in the treatment of duodenal ulcer, erosive esophagitis, and pathologic hypersecretory conditions (e.g., Zollinger-Ellison syndrome).
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