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Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is
Vasudevan G. Naidoo
doaj +5 more sources
Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study [PDF]
A case-control study comprising 1315 Campylobacter jejuni cases, 121 Campylobacter coli cases and 3409 frequency-matched controls was conducted in The Netherlands in 2002-2003. Risk factors for both C. jejuni and C.
Brandhof, W.E., van den+5 more
core +16 more sources
Hypocalcemia After Thyroidectomy in Patients Taking Proton Pump Inhibitors [PDF]
Objective Calcium homeostasis is regulated by the effects of parathyroid hormone (PTH) and vitamin D on the bones, GI tract, and kidneys. Post‐thyroidectomy hypoparathyroidism and resultant hypocalcemia are common complications associated with prolonged ...
Maxwell Rossip+3 more
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Proton-pump inhibitors and risk of renal disease [PDF]
Proton pump inhibitors (PPIs) are one group of drugs that inhibit gastric acid secretion by binding irreversibly to the gastric proton pump to the gastric proton pump.
Mahrang Hedaiaty+3 more
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Association between proton pump inhibitor therapy and clostridium difficile infection: a contemporary systematic review and meta-analysis. [PDF]
Introduction Emerging epidemiological evidence suggests that proton pump inhibitor (PPI) acid-suppression therapy is associated with an increased risk of Clostridium difficile infection (CDI).
A Deshpande+58 more
core +14 more sources
Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients. [PDF]
To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients.Multicenter prospective study.Acute geriatric medicine at the University Hospital of Nantes and the Hospital of ...
Anne Delcher+5 more
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(1) Background: Hepatic encephalopathy (HE) is a common complication in cirrhosis patients, and recently, clinical evidence indicates that a higher risk of HE is associated with the usage of proton pump inhibitors.
Pan Zhang+6 more
doaj +1 more source
Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics
BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz+7 more
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Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]
BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee+8 more
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Objectives Proton pump inhibitors, such as omeprazole and pantoprazole, are frequently prescribed for the treatment of acid reflux. However, those medications have been shown to affect a variety of physiologic processes, including bone homeostasis and ...
Bhavneet K. Chawla+3 more
doaj +1 more source