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Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is
Vasudevan G. Naidoo
doaj +4 more sources
Hypocalcemia After Thyroidectomy in Patients Taking Proton Pump Inhibitors [PDF]
Objective Calcium homeostasis is regulated by the effects of parathyroid hormone (PTH) and vitamin D on the bones, GI tract, and kidneys. Post‐thyroidectomy hypoparathyroidism and resultant hypocalcemia are common complications associated with prolonged ...
Maxwell Rossip +3 more
doaj +2 more sources
Deprescribing proton pump inhibitors
Kim Jun Kevin Teh +3 more
doaj +3 more sources
Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors
Proton Pump Inhibitors are used widely to manage many gastric acid-related conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett’s esophagus, Zollinger-Ellison syndrome, peptic ulcer disease, nonsteroidal anti-inflammatory drug ...
N. Maideen
semanticscholar +1 more source
AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review.
DESCRIPTION Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications ...
L. Targownik, D. Fisher, S. Saini
semanticscholar +1 more source
Simple Summary The current meta-analysis highlighted that proton pump inhibitors (PPIs) and histamine-2-receptor antagonists (H2RAs) could impact immune checkpoint inhibitors (ICIs) efficacy in NSCLC patients, highlighting the need for a deeper ...
Alessandro Rizzo +9 more
semanticscholar +1 more source
Proton Pump Inhibitors and Bone Health: An Update Narrative Review
Proton pump inhibitors (PPIs) are an antacid drug often used in acid-related disorders. They decrease acid secretion in the stomach by blocking an enzyme called H+/K+ ATPase which controls acid production.
E. Lespessailles, Toumi Hechmi
semanticscholar +1 more source
Proton pump inhibitors and risk of gastric cancer: population-based cohort study
Objective To determine whether new users of proton pump inhibitors (PPIs) are at an increased risk of gastric cancer compared with new users of histamine-2 receptor antagonists (H2RAs).
D. Abrahami +5 more
semanticscholar +1 more source
Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients. [PDF]
To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients.Multicenter prospective study.Acute geriatric medicine at the University Hospital of Nantes and the Hospital of ...
Anne Delcher +5 more
doaj +1 more source
Overprescribing proton pump inhibitors [PDF]
Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire +2 more sources

