Results 251 to 260 of about 54,280 (357)

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

open access: yesPROTEOMICS, Volume 26, Issue 5, Page 59-68, May 2026.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives   +7 more
wiley   +1 more source

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

open access: yesYeast, Volume 43, Issue 3, Page 77-88, May 2026.
ABSTRACT Given the biotechnological potential of yeast‐derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, Transcription Activator‐Like Effector Nucleases (TALENs), Zinc ...
Rodrigo Gonçalves Dias   +5 more
wiley   +1 more source

The receptor‐like pseudokinase LENG stimulates chilling tolerance in rice by inhibiting the activity of the OsCRPK1‐OsGF14d module

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 5, Page 1333-1348, May 2026.
The rice receptor‐like pseudokinase LENG enhances chilling tolerance by binding to and suppressing the kinase activity of OsCRPK1, thereby preventing OsCRPK1‐mediated phosphorylation of the cold‐tolerance positive regulator OsGF14d. ABSTRACT Cold damage during the seedling and reproductive stages has a pronounced impact on rice development and yield ...
Shuting Yuan   +12 more
wiley   +1 more source

Ustilago maydis Phosphatidic Acid and Phosphatidylserine‐Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy   +2 more
wiley   +1 more source

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