Results 171 to 180 of about 16,784 (210)

Negative Viral Load Follow-Up in an Untreated HIV-2 Infected Patient: A Case Report. [PDF]

open access: yesInfect Dis Clin Microbiol
Gür-Altunay D   +3 more
europepmc   +1 more source

Reduced bovine leukaemia virus proviral load in genetically resistant cattle

Animal Genetics, 1998
The bovine leukaemia virus (BLV) is an exogenous retrovirus that is closely related to the human T cell leukaemia viruses. Genetic resistance and susceptibility to persistent lymphocytosis (PL), an advanced subclinical stage of infection characterized by a polyclonal expansion of the infected B cell population, have been mapped to structural motifs in ...
M L, Mirsky   +3 more
openaire   +2 more sources

Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: High proviral load strongly predisposes to HAM/TSP

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1998
In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitative PCR method using a dual-labeled
M, Nagai   +10 more
openaire   +2 more sources

Low DNA HTLV-2 proviral load among women in São Paulo City

Virus Research, 2008
HTLV-2 infections are almost always asymptomatic, and diseases associated with the infection are rarely reported. Little information is available on the relationship between HTLV-2 proviral load and gender or expression of disease, especially among patients with HIV-1 co-infection.We studied 77 HTLV-2-infected subjects followed in our clinic for the ...
Patrícia, Montanheiro   +8 more
openaire   +2 more sources

HTLV-1 proviral load in cerebrospinal fluid may not be a good marker to differentiate asymptomatic carriers with high proviral load in blood from HAM/TSP patients

Journal of NeuroVirology, 2018
An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), although there is a considerable frequency of asymptomatic carriers (AC) with high PVL in blood. Our objective was to evaluate whether PVL quantified in cerebrospinal fluid (CSF)
Marina Lobato, Martins   +4 more
openaire   +2 more sources

Quantitation of HTLV-I proviral load by a TaqMan real-time PCR assay

Journal of Virological Methods, 2002
A quantitative real-time PCR assay was developed to measure the proviral load of human T-lymphotropic virus type I (HTLV-I) in peripheral blood mononuclear cells (PBMCs). The HTLV-I copy number was referred to the actual amount of cellular DNA by means of the quantitation of the albumin gene.
Axelle, Dehée   +8 more
openaire   +2 more sources

Differences in proviral DNA load between HIV-1- and HIV-2-infected patients

AIDS, 2008
The lesser pathogenicity of HIV-2 relative to HIV-1 is generally attributed to its slower replication. To compare the amounts of total HIV DNA during human HIV-1 and HIV-2 infection, we developed a quantitative real-time PCR method with a unique external quantification standard based on a single plasmid harboring both the HIV-1 and the HIV-2 LTR.Viral ...
Marie, Gueudin   +9 more
openaire   +2 more sources

Quantitative PCR for the measurement of circulating proviral load in HIV-infected individuals

Clinical and Diagnostic Virology, 1995
PCR has been applied extensively as a tool for the detection of HIV. We have previously developed a semi-quantitative microtiter plate assay for the specific detection of HIV PCR products.To develop and evaluate a novel quantitative assay for the measurement of circulating proviral load in HIV-infected individuals.We evaluated 70 consecutive ...
B, Conway, D S, Ko, D W, Cameron
openaire   +2 more sources

Monitoring of HTLV-1-associated diseases by proviral load quantification using multiplex real-time PCR

Journal of NeuroVirology, 2022
Proviral load (PVL) is one of the determining factors for the pathogenesis and clinical progression of the human T-lymphotropic virus type I (HTLV-1) infection. In the present study, we optimized a sensitive multiplex real-time PCR for the simultaneous detection and quantification of HTLV-1 proviral load and beta-globin gene as endogenous control.
Evandra Strazza Rodrigues   +9 more
openaire   +2 more sources

HIV-2-specific cytotoxic T-lymphocyte activity is inversely related to proviral load

AIDS, 1995
To characterize HIV-specific cytotoxic T-lymphocyte (CTL) activities in HIV-2-infected individuals and to relate these to HIV-2 proviral load.Peripheral blood mononuclear cells were collected from 16 HIV-2-seropositive and four HIV-1/2 dually seropositive subjects.
K, Ariyoshi   +6 more
openaire   +2 more sources

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