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Negative Viral Load Follow-Up in an Untreated HIV-2 Infected Patient: A Case Report. [PDF]
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Reduced bovine leukaemia virus proviral load in genetically resistant cattle
Animal Genetics, 1998The bovine leukaemia virus (BLV) is an exogenous retrovirus that is closely related to the human T cell leukaemia viruses. Genetic resistance and susceptibility to persistent lymphocytosis (PL), an advanced subclinical stage of infection characterized by a polyclonal expansion of the infected B cell population, have been mapped to structural motifs in ...
M L, Mirsky +3 more
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Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1998
In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitative PCR method using a dual-labeled
M, Nagai +10 more
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In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitative PCR method using a dual-labeled
M, Nagai +10 more
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Low DNA HTLV-2 proviral load among women in São Paulo City
Virus Research, 2008HTLV-2 infections are almost always asymptomatic, and diseases associated with the infection are rarely reported. Little information is available on the relationship between HTLV-2 proviral load and gender or expression of disease, especially among patients with HIV-1 co-infection.We studied 77 HTLV-2-infected subjects followed in our clinic for the ...
Patrícia, Montanheiro +8 more
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Journal of NeuroVirology, 2018
An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), although there is a considerable frequency of asymptomatic carriers (AC) with high PVL in blood. Our objective was to evaluate whether PVL quantified in cerebrospinal fluid (CSF)
Marina Lobato, Martins +4 more
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An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), although there is a considerable frequency of asymptomatic carriers (AC) with high PVL in blood. Our objective was to evaluate whether PVL quantified in cerebrospinal fluid (CSF)
Marina Lobato, Martins +4 more
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Quantitation of HTLV-I proviral load by a TaqMan real-time PCR assay
Journal of Virological Methods, 2002A quantitative real-time PCR assay was developed to measure the proviral load of human T-lymphotropic virus type I (HTLV-I) in peripheral blood mononuclear cells (PBMCs). The HTLV-I copy number was referred to the actual amount of cellular DNA by means of the quantitation of the albumin gene.
Axelle, Dehée +8 more
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Differences in proviral DNA load between HIV-1- and HIV-2-infected patients
AIDS, 2008The lesser pathogenicity of HIV-2 relative to HIV-1 is generally attributed to its slower replication. To compare the amounts of total HIV DNA during human HIV-1 and HIV-2 infection, we developed a quantitative real-time PCR method with a unique external quantification standard based on a single plasmid harboring both the HIV-1 and the HIV-2 LTR.Viral ...
Marie, Gueudin +9 more
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Quantitative PCR for the measurement of circulating proviral load in HIV-infected individuals
Clinical and Diagnostic Virology, 1995PCR has been applied extensively as a tool for the detection of HIV. We have previously developed a semi-quantitative microtiter plate assay for the specific detection of HIV PCR products.To develop and evaluate a novel quantitative assay for the measurement of circulating proviral load in HIV-infected individuals.We evaluated 70 consecutive ...
B, Conway, D S, Ko, D W, Cameron
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Journal of NeuroVirology, 2022
Proviral load (PVL) is one of the determining factors for the pathogenesis and clinical progression of the human T-lymphotropic virus type I (HTLV-1) infection. In the present study, we optimized a sensitive multiplex real-time PCR for the simultaneous detection and quantification of HTLV-1 proviral load and beta-globin gene as endogenous control.
Evandra Strazza Rodrigues +9 more
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Proviral load (PVL) is one of the determining factors for the pathogenesis and clinical progression of the human T-lymphotropic virus type I (HTLV-1) infection. In the present study, we optimized a sensitive multiplex real-time PCR for the simultaneous detection and quantification of HTLV-1 proviral load and beta-globin gene as endogenous control.
Evandra Strazza Rodrigues +9 more
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HIV-2-specific cytotoxic T-lymphocyte activity is inversely related to proviral load
AIDS, 1995To characterize HIV-specific cytotoxic T-lymphocyte (CTL) activities in HIV-2-infected individuals and to relate these to HIV-2 proviral load.Peripheral blood mononuclear cells were collected from 16 HIV-2-seropositive and four HIV-1/2 dually seropositive subjects.
K, Ariyoshi +6 more
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