Expression of lymphatic markers in the adult rat spinal cord
Frontiers in Cellular Neuroscience, 2016 Under physiological conditions, lymphatic vessels are thought to be absent from the central nervous system (CNS), although they are widely distributed within the rest of the body. Recent work in the eye, i.e.
Alexandra eKaser-Eichberger +18 more
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An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype [PDF]
, 2002 Jeffrey T. Wigle
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Nature Communications, 2018 VEGFC, its receptor FLT4, and transcriptional effector PROX1 control formation of the lymphatic system but how is unclear. Here, the authors show that the transcription factor hematopoietically expressed homeobox (HHEX) regulates VEGFC, FLT4 and PROX1 in
Sébastien Gauvrit +13 more
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A Homeobox Protein, Prox1, Is Involved in the Differentiation, Proliferation, and Prognosis in Hepatocellular Carcinoma [PDF]
, 2006 Masayuki Shimoda +5 more
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An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides
Nature Communications, 2017 HDAC3 is a critical mediator of hepatic lipid metabolism and its loss leads to fatty liver. Here, the authors characterize the liver HDAC3 interactome in vivo, provide evidence that HDAC3 interacts with PROX1, and show that HDAC3 and PROX1 control ...
Sean M. Armour +7 more
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Developmental and pathological lymphangiogenesis: from models to human disease [PDF]
, 2018 The lymphatic vascular system, the body's second vascular system present in vertebrates, has emerged in recent years as a crucial player in normal and pathological processes.
Maby-El Hajjami, Hélène +1 more
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Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner
Physiological ReportsThe lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich +5 more
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Characterization of Prox1 and VEGFR-3 Expression and Lymphatic Phenotype in Normal Organs of Mice Lacking p50 Subunit of NF-κB [PDF]
, 2010 Michael J. Flister +2 more
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Cis-regulatory control of the SM50 gene, an early marker of skeletogenic lineage specification in the sea urchin embryo [PDF]
, 1995 The SM50 gene encodes a minor matrix protein of the sea urchin embryo spicule. We carried out a detailed functional analysis of a cis-regulatory region of this gene, extending 440 bp upstream and 120 bp downstream of the transcription start site, that ...
Britten, Roy J. +3 more
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An Algorithm for Cellular Reprogramming
, 2017 The day we understand the time evolution of subcellular elements at a level of detail comparable to physical systems governed by Newton's laws of motion seems far away.
Bloch, Anthony +7 more
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