Results 21 to 30 of about 9,468 (203)
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. [PDF]
PLoS Pathogens, 2012 Lymphatic endothelial cells (LECs) are differentiated from blood vascular endothelial cells (BECs) during embryogenesis and this physiological cell fate specification is controlled by PROX1, the master regulator for lymphatic development.
Jaehyuk Yoo +14 more
doaj +1 more source
Penile cavernous sinusoids are Prox1-positive hybrid vessels
Vascular Biology, 2023 Abstract Endothelial cells (ECs) of blood and lymphatic vessels have distinct identity markers that define their specialized functions. Recently, specialized hybrid vasculatures with both blood and lymphatic vessel-specific features have been discovered in multiple tissues.
Sarah Schnabellehner +4 more
openaire +4 more sources
Expression of Prox1 during mouse cochlear development [PDF]
Journal of Comparative Neurology, 2006 AbstractWe carried out an analysis of the expression of Prox1, a homeodomain transcription factor, during mouse inner ear development with particular emphasis on the auditory system. Prox1 is expressed in the otocyst beginning at embryonic day (E)11, in the developing vestibular sensory patches.
Olivia, Bermingham-McDonogh +5 more
openaire +2 more sources
PROX1 Is Associated with Cancer Progression and Prognosis in Gastric Cancer [PDF]
Anticancer Research, 2018 It was recently reported that expression of prospero homeobox protein-1 (PROX1) is correlated with the prognosis of esophageal cancer and colorectal cancer. However, its correlation with gastric cancer is unclear.Our study analyzed the effect of PROX1 knockdown on the migration, invasion and proliferation of the MKN45 human gastric cancer cell line ...
Koji, Ueta +3 more
openaire +2 more sources
Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3 [PDF]
Open Biology, 2019 Gata3 is a DNA-binding transcription factor involved in cellular differentiation in a variety of tissues including inner ear, hair follicle, kidney, mammary gland and T-cells. In a previous study in 2009, Maeda et al. (Dev. Dyn.
Elena Martynova +4 more
doaj +1 more source
, 2021 (A) Paraffin-embedded sections of Kaposi sarcoma (KS) lesions from three AIDS-KS patients were analyzed by immunohistochemistry (IHC) staining (400x and enlarged) for PROX1 and LANA.
Zhengzhou Lu (11402525) +4 more
core +1 more source
A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]
, 2010 The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios +7 more
core +1 more source
Role of Prox1 in the Transforming Ascending Thin Limb of Henle's Loop during Mouse Kidney Development. [PDF]
PLoS ONE, 2015 The homeobox transcription factor Prox1 is critical to the development of many embryonic organs and tissues, although current understanding of its expression in the developing renal medulla is limited.
Yu-Mi Kim +7 more
doaj +1 more source
Prox1 maintains muscle structure and growth in the developing heart [PDF]
Development, 2009 Impaired cardiac muscle growth and aberrant myocyte arrangement underlie congenital heart disease and cardiomyopathy. We show that cardiac-specific inactivation of the murine homeobox transcription factor Prox1 results in the disruption of expression and localisation of sarcomeric proteins, gross myofibril disarray and growth-retarded hearts ...
Risebro, Catherine A. +13 more
openaire +6 more sources
PLoS ONE, 2022 PurposeGreater muscle fragility is thought to cause the exhaustion of the muscle stem cells during successive degeneration/repair cycles, leading to muscle wasting and weakness in Duchenne muscular dystrophy.
Alexandra Monceau +7 more
doaj +2 more sources