Results 291 to 300 of about 684,958 (347)
Pik3c3 expression profiling in the mouse kidney and its role in proximal tubule cell physiology.
Am J Physiol Cell PhysiolLiu T +10 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Interactions of vitamin D and the proximal tubule
Pediatric Nephrology, 2015Severe vitamin D deficiency (reduction in serum 25(OH)D concentration) in infants and children can cause features of the Fanconi syndrome, including phosphaturia, glycosuria, aminoaciduria, and renal tubular acidosis. This indicates that vitamin D and its metabolites influence proximal tubule function.
R. Chesney
openaire +3 more sources
Development of a microphysiological model of human kidney proximal tubule function
Kidney International, 2016 The kidney proximal tubule is the primary site in the nephron for excretion of waste products through a combination of active uptake and secretory processes, and is also a primary target of drug-induced nephrotoxicity.
Catherine K Yeung +2 more
exaly +2 more sources
Frontiers in Physiology, 2017 Due to its exposure to high concentrations of xenobiotics, the kidney proximal tubule is a primary site of nephrotoxicity and resulting attrition in the drug development pipeline.
Deborah G Nguyen
exaly +2 more sources
Disorders of the Renal Proximal Tubule
Nephron Physiology, 2010Following glomerular filtration, the bulk of solutes are reabsorbed in the proximal tubule to prevent excessive losses of vital metabolites. In this nephron segment, reabsorption is largely active via dedicated transporters. Hereditary defects in proximal tubular function are characterized by malabsorption affecting amino acids, glucose, potassium ...
Bokenkamp, A., Ludwig, M.
openaire +3 more sources
Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction
European Journal of Pharmacology, 2016Martijn J Wilmer
exaly +2 more sources
1979
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
M, Silverman, R J, Turner
openaire +2 more sources
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
M, Silverman, R J, Turner
openaire +2 more sources
Functional Ultrastructure of the Proximal Tubule
Comprehensive Physiology, 1991Abstract The sections in this article are: Location of Proximal Tubule Fixation of Proximal Tubule Cells for Electron Microscopy Ultrastructure of the Mammalian Proximal Tubule Cell
Maunsbach, Arvid B. +1 more
openaire +2 more sources
Endocytic Receptors in the Renal Proximal Tubule
Physiology, 2012Protein reabsorption is a predominant feature of the renal proximal tubule. Animal studies show that the ability to rescue plasma proteins relies on the endocytic receptors megalin and cubilin. Recently, studies of patients with syndromes caused by dysfunctional receptors have supported the importance of these for protein clearance of human ...
Christensen, Erik Ilsø +4 more
openaire +2 more sources
Oxalate secretion in the rat proximal tubule
American Journal of Physiology-Renal Physiology, 1981Simultaneous capillary and luminal microperfusion studies in the proximal convoluted tubule of the rat were performed to examine the transepithelial secretory flux of [14C]oxalate. Increases in the concentration of oxalate in the capillary solution from 0.096 to 4.3 mM resulted in progressively higher rates of oxalate secretion into the lumen. Further
T F, Knight +3 more
openaire +2 more sources